Intrahepatic Cholestasis of Pregnancy (ICP) Is A Liver Disease That Occurs During Pregnancy

Abstract

Many diseases in newborns and young children have a chronic progressive course, leading to biliary cirrhosis, formation of liver failure and early liver transplantation (LT). Nutritional status is an important prognostic indicator of morbidity and mortality in patients before and after LT. Thus, malnutrition syndrome and negative nitrogen balance have been shown to be negative prognostic indicators of overall survival in CKD patients [ 7 , 8 ]. In addition, long-term malnutrition in young children with cholestasis syndrome leads to slow brain growth, impaired psychomotor development, and decreased resistance to infections. In children with biliary atresia before transplantation, the level of malnutrition was found to be a predictor of cognitive performance in the years after transplantation [9].