Clinical and Genetic Features of Unstable Angina Pectoris Depending on Various Psychosocial Risk Factors
Keywords:
Unstable angina pectoris, uric acid, anxiety-depressive syndrome, cytokine imbalance, polymorphisms of IL-1β T/C 511 and IL-10 C/T 819 genesAbstract
In our study we investigated the association of several biopsychosocial risk factors on the progression of unstable angina pectoris, in particular blood uric acid level, cytokine imbalance, anxiety-depressive syndrome, polymorphism of proinflammatory genes, and basic lipid spectrum parameters. We analyzed the correlation between the studied MC parameters, anxiety parameters, production of immunoregulatory cytokines, polymorphism of proinflammatory genes IL-1β T/C 511 (rs16944) and IL-10 T/C 819 (rs1800871), as well as cholesterol metabolism parameters.
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