Diagnosis of Sensitization in Allergic Diseases
Keywords:
respiratory allergy, allergic diseases, sensitization, diagnosis, testAbstract
Symptoms of respiratory allergies not only affect the quality of life of patients, but also increase healthcare costs due to the appointment of unnecessary, sometimes expensive studies, which is primarily due to the lack of knowledge of internists about the causes and mechanisms of disorders that occur in patients with allergies. The article is devoted to the differential diagnosis of allergic diseases depending on allergic sensitization, which contributes to improving the quality of preventive allergological, gastroenterological and therapeutic services with a subsequent reduction in morbidity and disability.
References
Rael E.L., Lockey R.F. Interleukin-13 signaling and its role in asthma. World Allergy Organ. J., 2015, Vol. 4, no. 3, pp. 54-64.
Rodríguez CL, Shah SA, Stokholm J. The infant gut virome is associated with preschool asthma risk independently of bacteria. Nat Med. 2023;1-11. Available from: doi:10.1038/s41591-022-00001-3.
Silva IS, Almeida AD, Klein A. Platelet-activating factor and protease-activated receptor 2 cooperate to promote neutrophil recruitment and lung inflammation through nuclear factor-kappa B transactivation. Sci Rep. 2023;13(1):21637. Available from: doi:10.1038/s41598-022-00002-1.
Tregoning JS, Schwarze J. Respiratory viral infections in infants: causes, clinical symptoms, virology, and immunology. Clin Microbiol Rev 2015; 23 (1): 74–98. DOI: 10.1128/cmr.00032-09.
Tutino M, Hankinson J, Curtin JA. Identification of differences in CD4 + T-cell gene expression between people with asthma and healthy controls. Sci Rep. 2023;13(1):22796. Available from: doi:10.1038/s41598-022-00001-2.
Zhang H, Xue K, Sun L. Cullin5 drives experimental asthma exacerbations by modulating alveolar macrophage antiviral immunity. Nat Commun. 2024;15(1):252. Available from: doi:10.1038/s41467-023-00002-3.
Zhu S, Qian Y. IL-17/IL-17 receptor system in autoimmune disease: mechanisms and therapeutic potential. Clin Sci. 2017;122(11):487–511. DOI: http://dx.doi.org/10.1042%2FCS20110496, Gaffen SL. Structure and signalling in the IL-17 receptor family. Nat Rev Immunol. 2019;9(8):556–67. DOI: http://dx.doi.org/10.1038%2Fnri2586
