Parameters of the Immune System in Children with Atopic Dermatitis
Keywords:
Atopic dermatitis, immune system, IgE, IL-5, IL-13, TGF- β, eotaxin.Abstract
Atopic dermatitis is a chronic, relapsing inflammatory skin disease with pathogenesis involving genetic predisposition, immunological and epidermal barrier dysfunction, and environmental factors. The main symptom is attention; Skin rashes range from mild erythema to mild lichenification and erythroderma. Diagnosis includes taking a history and causes. Treatment includes recommendations for proper skin care, avoidance of triggers, and topical use of corticosteroids and immunosuppressants. Treatment of itching and superinfections is also important. In severe cases, systemic immunosuppressive therapy may be required. Atopic dermatitis that develops in childhood often regresses or its symptoms become significantly less severe in adulthood.