Prognostic Value Of Ki67 In Patients With Locally Advanced Cervical Cancer
Abstract
A study conducted in patients with locally advanced cervical cancer showed that a high level of expression of the Ki67 proliferation marker in primary patients after neoadjuvant chemotherapy correlated with an unfavorable prognosis, which makes it possible to use these indicators in monitoring the course of the disease. It was shown that before the start of antitumor treatment, the level of Ki67 expression was as high as possible in those patients who subsequently experienced disease progression, and reached 85%. It was revealed that in patients with locally advanced cervical cancer with an expression level of Ki67<50%, the indicators of 5-year overall survival are statistically significantly higher than in patients with locally advanced cervical cancer with an expression level of Ki67>50%.
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