Mechanisms of Nerve Impulse Transmission and their Role in Nervous System Diseases

Authors

  • Rashidova Rukhshona 2nd year student at Zarmed University
  • Vakhidova Adola Mamatkulova Supervisor: Dsc of biology, associate professor

Keywords:

Nerve impulse, neurotransmission, epilepsy, multiple sclerosis, ion channels, myelin sheath, neurological disorders

Abstract

Nerve impulse transmission is a fundamental process by which the nervous system communicates and reacts to internal and external stimuli. This intricate system relies on various elements, including ion channels, neurotransmitters, and myelin sheaths. Dysfunctions in these processes can lead to significant health challenges, including neurological disorders such as epilepsy and multiple sclerosis. This article explores the mechanisms underlying nerve impulse transmission and examines how disruptions in these mechanisms contribute to the development and progression of neurological diseases.

References

Kandel, E. R., Schwartz, J. H., & Jessell, T. M. (2013). Principles of Neural Science (5th ed.). McGraw-Hill.

Olsson, T. et al. (2016). “Multiple sclerosis: recent advances in the treatment.” Nature Reviews. Drug Discovery, 15(3), 241-259.

Engel, J. (2011). “The development of epilepsy: a historical perspective.” Clinical Neurophysiology, 122(11), 2202-2210.

Rees, S. (2012). “Neurotransmitters in Health and Disease.” Neuroscience & Biobehavioral Reviews, 36(4), 1207-1220.

Hwang, Y. C., et al. (2020). “Neuroinflammation in multiple sclerosis: immune mechanisms and therapeutic targets.” Journal of Neuroinflammation, 17(1), 150.

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Published

2024-10-16

How to Cite

Rukhshona, R., & Mamatkulova, V. A. (2024). Mechanisms of Nerve Impulse Transmission and their Role in Nervous System Diseases. International Journal of Integrative and Modern Medicine, 2(10), 138–140. Retrieved from https://medicaljournals.eu/index.php/IJIMM/article/view/1051