The Relationship of Hepatobiliary System Dysfunction with Covid-19

The World Health Organization has repeatedly stated that coronavirus mainly affects the lower respiratory tract, but did not deny that in severe cases of the disease, multisystem damage may occur. However, patients began to develop a variety of symptoms of this infection: from asymptomatic to severe clinical symptoms, critical conditions, symptoms of acute distress, acute respiratory failure, multiple organ failure and, ultimately, death [52]. In patients infected with the virus, the clinical manifestations were different, there were many extrapulmonary symptoms, including liver damage [58]. According to a group of articles by hepatologists, when evaluating a systematic meta-analysis in patients, the level of liver damage is associated with a severe or mild course of the disease [53].