Morphological Changes in the Heart in Metabolic Syndrome and their Implications for Cardiovascular Health

Abstract

Metabolic syndrome (MetS) is a cluster of interrelated risk factors that increase the likelihood of developing cardiovascular diseases (CVD). Among its various components, alterations in cardiac morphology are becoming increasingly recognized as significant contributors to cardiovascular dysfunction. This article examines the morphological changes in the heart that occur in the context of MetS, including left ventricular hypertrophy, increased myocardial fibrosis, and altered chamber dimensions. We also explore the pathophysiological mechanisms underlying these changes, such as insulin resistance, chronic inflammation, and oxidative stress, and their effects on myocardial structure and function. The implications of these changes for cardiovascular health are discussed, emphasizing the need for early detection and targeted therapeutic strategies. Understanding the relationship between metabolic syndrome and cardiac morphology is crucial for improving cardiovascular outcomes and managing MetS-associated heart disease.