Studying Liver Elastometry Parameters in Patients with Chronic Viral Hepatitis C with Extrahepatic Manifestations

The purpose of the study. A retrospective analysis of 319 adult patients aged 18 to 71 years with HCV
caused by HCV genotypes 1, 2, 3 who were treated at the Bukhara OIB in the period from 2018 to 2020
was carried out. The main group of patients with fibrotic processes of the F2-F3 stage was 74.1%, and
the control group of patients with the F1–F2 stage of fibrotic lesion was 63.8%. Fibrotic lesions of the
F0 – F1 stage in the main group amounted to 21.4%, and in the control group 47.9% of cases.
Cryoglobulinemic vasculitis was observed in 34.8% of cases, among its manifestations: arthritis 28.2%,
hemorrhagic vasculitis 46.2%, peripheral neuropathy 15.4%, chronic glomerulonephritis 5.1%. 2 cases
of B-cell lymphoma have been reported in female patients at the stage of liver cirrhosis.