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Analysis of the Relevance and Necessity of Studying the System of Centralization of Clinical Diagnostic Laboratory Tests

Vol. 3 No. 9 (2025): International Journal of Integrative and Modern Medicine:

O. A. Aripov (1), M. M. Khojimurod (2)

(1) The Center for the Development of professional qualifications of medical workers, Uzbekistan
(2) The Center for the Development of professional qualifications of medical workers, Uzbekistan
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Abstract:

Medical laboratories (MLs), which improve diagnostic precision and aid in clinical decision-making, are essential to the delivery of healthcare worldwide. The various contributions of machine learning (ML) are examined in this systematic review, with a focus on their significance in disease surveillance, pandemic preparedness, and the integration of cutting-edge technologies like artificial intelligence (AI). Medical laboratories provide vital diagnostic services to detect diseases like infections, metabolic abnormalities, and cancers, making them equally important to clinical procedures. By examining patient samples, they track the efficacy of treatments, allowing medical professionals to improve treatments. They also improve patient care by ensuring test accuracy through stringent quality control procedures and promoting customized medicine by customizing therapies based on genetic and molecular data. The cost of medical laboratory testing is frequently cited as the test's value, but the tests' clinical advantages are just as significant. Clinical outcome is influenced by laboratory testing, which is widely recognized to play a part in clinical decision making. Therefore, the importance of laboratory testing should be weighed against how it influences positive behaviors and results. This covers both the testing phase, which involves selecting tests that may impact clinical decision-making and the reporting phase, which directs clinical decisions and actions. If clinical decision support software and systems are focused on supporting clinical decisions addressing patient outcomes that are supported by evidence or consensus, they can increase the value of medical laboratory tests. In order to improve laboratory services and make sure they are available, effective, and able to satisfy the changing needs of healthcare systems, this evaluation emphasizes the importance of stakeholders working together. Overall, the results support the deployment of cutting-edge technology and improved laboratory infrastructures to enhance health outcomes worldwide.

References

1. Sikaris KA. Enhancing the Clinical Value of Medical Laboratory Testing. Clin Biochem Rev. 2017 Nov;38(3):107-114.

2. Chaudhry AS, Inata Y, Nakagami-Yamaguchi E. Quality analysis of the clinical laboratory literature and its effectiveness on clinical quality improvement: a systematic review. J Clin Biochem Nutr. 2023 Sep;73(2):108-115. doi: 10.3164/jcbn.23-22.

3. Adekoya A, Okezue MA, Menon K. Medical Laboratories in Healthcare Delivery: A Systematic Review of Their Roles and Impact. Laboratories. 2025; 2(1):8.

https://doi.org/10.3390/laboratories2010008

4. Munagandla, V.B.; Dandyala, S.S.V.; Vadde, B.C. AI-Powered Cloud-Based Epidemic Surveillance System: A Framework for Early Detection. Rev. Intel. Artif. Med. 2024, 15, 673–690.

5. Chintala, S.K. AI in public health: Modeling disease spread and management strategies. NeuroQuantology 2022, 20, 10830.

6. Shiwlani, A.; Khan, M.; Sherani AM, K.; Qayyum, M.U.; Hussain, H.K. Revolutionizing healthcare: The impact of artificial intelligence on patient care, diagnosis, and treatment. Jurihum J. Inov. Dan Hum. 2024, 1, 779–790.

7. da Silva, S.J.R.; Silva, C.T.A.D.; Guarines, K.M.; Mendes, R.P.G.; Pardee, K.; Kohl, A.; Pena, L. Clinical and laboratory diagnosis of SARS-CoV-2, the virus causing COVID-19. ACS Infect. Dis. 2020, 6, 2319–2336.

8. Verma, A.; Gupta, R. Role of Medical Laboratory Technology in Health Care. In Clinical Laboratory Management; Springer: Berlin/Heidelberg, Germany, 2024; pp. 3–6.

9. Santarsiero, F.; Schiuma, G.; Carlucci, D.; Helander, N. Digital transformation in healthcare organisations: The role of innovation labs. Technovation 2023, 122, 102640.

10. Pradhan, S.; Gautam, K.; Pant, V. ISO 15189: 2022; what’s new in new? J. Pathol. Nepal 2023, 13, 2027–2028.

11. Sayed, S.; Cherniak, W.; Lawler, M.; Tan, S.Y.; El Sadr, W.; Wolf, N.; Silkensen, S.; Brand, N.; Looi, P.L.M.; Pai, S.A.; et al. Improving pathology and laboratory medicine in low-income and middle-income countries: Roadmap to solutions. Lancet 2018, 391, 1939–1952.

12. Chowdhury, A.T.; Newaz, M.; Saha, P.; Majid, M.E.; Mushtak, A.; Kabir, M.A. Application of Big Data in Infectious Disease Surveillance: Contemporary Challenges and Solutions. In Surveillance, Prevention, and Control of Infectious Diseases: An AI Perspective; Springer: Berlin/Heidelberg, Germany, 2024; pp. 51–71.

13. Kumar, Y.; Koul, A.; Singla, R.; Ijaz, M.F. Artificial intelligence in disease diagnosis: A systematic literature review, synthesizing framework and future research agenda. J. Ambient. Intell. Humaniz. Comput. 2023, 14, 8459–8486.

14. Sautter, R.; Halstead, D. The importance of medical laboratory scientists and the number of doctoral scientists that began their career by working on the front lines of laboratory medicine. Lab. Med. 2023, 54, e121–e123.

15. Church, D.L.; Naugler, C. Using a systematic approach to strategic innovation in laboratory medicine to bring about change. Crit. Rev. Clin. Lab. Sci. 2022, 59, 178–202.

16. Panteghini, M. Redesigning the surveillance of in vitro diagnostic medical devices and medical laboratory performance by quality control in the traceability era. Clin. Chem. Lab. Med. 2023, 61, 759–768.

17. Durant, T.J.S.; Peaper, D.R.; Ferguson, D.; Schulz, W.L. Impact of COVID-19 pandemic on laboratory utilization. J. Appl. Lab. Med. 2020, 5, 1194–1205.

18. Ahn, C.; Amer, H.; Anglicheau, D.; Ascher, N.; Baan, C.; Battsetset, G.; Bat-Ireedui, B.; Berney, T.; Betjes, M.; Bichu, S.; et al. Global Transplantation COVID Report March 2020. Transplantation 2020, 104, 1974–1983.

19. Proksch, M.; Paliwal, N.; Bielert, W. The Secrets of AI Value Creation: A Practical Guide to Business Value Creation with Artificial Intelligence from Strategy to Execution; John Wiley & Sons: Hoboken, NJ, USA, 2024.

20. Challoumis, C. Building a sustainable economy-how ai can optimize resource allocation. In Proceedings of the XVI International Scientific Conference, Philadelphia, PA, USA, 3–4 October 2024.

21. Kong, J.D.; Akpudo, U.E.; Effoduh, J.O.; Bragazzi, N.L. Leveraging Responsible, Explainable, and Local Artificial Intelligence Solutions for Clinical Public Health in the Global South. Healthcare 2023, 11, 457.