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Deciphering Anticholinesterase Agents: Mechanistic Insights and Clinical

Vol. 3 No. 10 (2025): International Journal of Integrative and Modern Medicine:

Hodiyev Khushnudbek Ahmad ugli (1)

(1) Asia International University, Bukhara, Uzbekistan, Uzbekistan
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Abstract:

Anticholinesterase agents are a vital class of drugs in pharmacology that inhibit the enzyme acetylcholinesterase, resulting in increased concentrations of acetylcholine at synaptic junctions. This action enhances cholinergic transmission, affecting both the central and peripheral nervous systems. These agents have profound clinical importance in treating conditions such as myasthenia gravis, Alzheimer’s disease, glaucoma, and in reversing the effects of neuromuscular blockers during surgery. This paper explores their mechanism of action, classification, pharmacodynamics, and therapeutic applications.

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