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Influence of Hormonal and Intrauterine Contraceptive Methods on Cervical Health and Hpv-Related Changes

Vol. 3 No. 11 (2025): International Journal of Integrative and Modern Medicine:

Atakhodjaeva F. A. (1), Tashbaeva U. I. (2)

(1) Associate Professor, Tashkent State Medical University, Tashkent, Uzbekistan, Uzbekistan
(2) Master’s degree, Tashkent State Medical University, Tashkent, Uzbekistan, Uzbekistan
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Abstract:

Cervical cancer remains one of the most common malignancies among women worldwide. Persistent infection with high-risk human papillomavirus (hrHPV) types is the primary etiological factor. Despite the effectiveness of HPV vaccination and cervical screening, the burden of disease remains high, particularly in low- and middle-income countries. The influence of contraceptive methods—especially combined oral contraceptives (COCs) and intrauterine devices (IUDs)—on cervical epithelial health and HPV-related pathology continues to be debated. This study is conducted to evaluate the potential relationship between the use of COCs and IUDs and the occurrence of cervical epithelial and microbiological alterations, including inflammatory and dysplastic changes, in women of reproductive age.

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