Abstract:

This article examines modern approaches to improving bone regeneration efficiency in cases of pronounced alveolar atrophy of the jaws. A comparative study of the use of traditional auto transplantation and innovative technologies, including the use of osteoplastic materials based on β-tricalcium phosphate, platelet-rich plasma (PRP), and composite systems with mesenchymal stem cells (MSC) and growth factor VEGF, was conducted. The study included 60 patients with II-III-degree alveolar ridge atrophy.

The results showed that the use of biomaterials activated by PRP and MSC accelerates angiogenesis, increases the degree of osseointegration of implants, and reduces the frequency of inflammatory complications compared to classical auto transplantation. The average effectiveness of intergeneration was 90-95% when using combined technologies, compared to 80% in the control group.

The integration of digital methods - navigation surgery, 3D planning, and bioprinting - increases the accuracy of transplant positioning, optimizes bone bed geometry, and improves the prediction of implantation outcomes.

Thus, the use of advanced biotechnological and digital solutions provides a new quality of bone augmentation, increasing the reproducibility and clinical effectiveness of procedures in patients with pronounced atrophy of the alveolar processes.