The Impact of Antibacterial Therapy on Clinical Outcomes and Intestinal Microbiota in Children with Acute Bacterial Diarrhea
DOI:
https://doi.org/10.31149/ijimm.v4i2.2695Keywords:
acute intestinal infections (AII), children, antibiotic resistance, antibacterial therapy, microbiota, etiotropic treatment, treatment optimization, pathogensAbstract
The constant variability of microbial sensitivity to widely used antibiotics and the rise of antibiotic-resistant strains of pathogens in acute intestinal infections necessitate the use of antibacterial drugs that demonstrate the highest sensitivity to the identified pathogen while minimizing side effects [6, 8, 9]. Acute intestinal infections (AII) remain one of the most prevalent infectious pathologies in childhood, accompanied by significant morbidity and a high risk of complications [1, 2]. Alterations in the composition of the microbiota can negatively impact a child's immune status and contribute to an increased frequency of recurrent intestinal infections [7, 8].
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