MORPHOLOGICAL CHANGES OF ADENOID VEGETATION IN RHINOSINUSITIS

Abstract

This study explores the morphological changes of adenoid vegetation in patients with rhinosinusitis. Chronic rhinosinusitis induces significant hypertrophy of the adenoid tissue, marked by an increased number and size of lymphoid follicles. Histopathological analysis reveals notable hyperplasia of the lymphoid tissue, accompanied by infiltration of inflammatory cells such as lymphocytes, plasma cells, and macrophages. Additionally, fibrotic changes and alterations in the surface epithelium, including metaplasia and ulceration, are commonly observed due to persistent infection and inflammation. These morphological changes are closely associated with clinical symptoms like nasal obstruction, recurrent infections, and impaired nasal breathing. Recognizing these alterations is essential for devising effective treatment strategies, including both medical management and surgical intervention, to alleviate inflammation and prevent symptom recurrence. This study underscores the importance of understanding the morphological dynamics of adenoid vegetation in rhinosinusitis to enhance diagnostic accuracy and therapeutic outcomes for affected patients.