Assessment of Tuberculosis Treatment Strategies in HIV Patients: A Comparative Study of Two Healthcare Facilities in Oyo State, Nigeria

Authors

  • Obeka, Maxwell Okoroafor
  • Adeniran Adeniyi Ayobami Babcock University, Ilishan-Remo, Ogun State

Abstract

Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) co-infection, particularly prevalent in Sub-Saharan Africa, significantly increases morbidity and mortality rates. The synergistic relationship between TB and HIV, often termed 'the cursed duet,' exacerbates the global health burden by elevating the risk of developing active TB among HIV-infected individuals. This co-infection accelerates disease progression, complicates treatment protocols, and strains healthcare systems. In Nigeria, a country ranking sixth globally in TB burden, the intersection of HIV and TB presents formidable public health and socio-economic challenges. Effective management of HIV/TB co-infection is critical to reducing morbidity and mortality, alleviating healthcare system burdens, and mitigating the economic impact on affected communities.

References

Adebayo, A. M., Adeniyi, B. O., Oluwasanu, M., Hassan, A., Ajuwon, G. A., Ogbuji, Q. C., Adewole, D., Osho, A. J., Olukolade, R., Ladipo, O. A., & Ajuwon, A. J. (2020). Tuberculosis treatment outcomes and associated factors in two states in Nigeria.

Corbett, C. E. (2003). HIV-TB co-infection: Epidemiology, diagnosis and management. Indian Journal of Medical Research, 121(4), 480-495.

Ejikeme, N., & Peter, G. A. (2010). Prevalence of Mycobacterium tuberculosis and human immunodeficiency virus (HIV) infections in Umuahia, Abia State, Nigeria. African Journal of Microbiology Research, 4(14), 1486-1490.

Federal Ministry of Health. (2000). Tuberculosis and leprosy control efforts in Nigeria. National Tuberculosis and Leprosy Control Programme (NTBLCP), 150.

Griffith, D., & Kerr, C. (1996). Tuberculosis: Disease of the past, disease of the present. Journal of Perianesthesia Nursing, 11(4), 240–245.

Harries, A. D. (1990). Tuberculosis and HIV infection in developing countries. The Lancet, 1, 387-390.

Idigbe, E. O., Nasidi, A., Anyiwo, C. E., Onubogu, C., Alabi, S., Okoye, R., Ugwu, O., & John, E. K. (1994). Prevalence of human immunodeficiency virus antibodies in tuberculosis patients in Lagos, Nigeria. Journal of Tropical Medicine and Hygiene, 97(2), 91-97.

Idowu, A. A., Oluwasegun, A. A., Michael, O., Olatunde-Aiyedun, T. G., & Jacob, O. N. (2021). Prevalence and the risk factors associated with HIV-TB co-infection among clinic attendees in DOTS and ART centres in Ibadan, Nigeria. Central Asian Journal of Medical and Natural Science, 2(3), 73-87. https://doi.org/10.17605/cajmns.v2i3.177

International Union Against Tuberculosis and Lung Disease (IUATLD). (2000). TB and HIV in: Management of TB, A guide for low-income countries (15th ed.), 12.

Knoll, B., Lassmann, B., & Temesgen, Z. (2007). Current status of HIV infection: A review for non-HIV treating physicians. International Journal of Dermatology, 46(12), 1219–1228.

Olaniran, O., Hassan-Olajokun, R. E., Oyovwevotu, M. A., & Agunlejika, R. A. (2011). Prevalence of tuberculosis among HIV/AIDS patients in Obafemi Awolowo University Teaching Hospital Complex (OAUTHC), Ile-Ife. International Journal of Biological and Medical Research, 2(4), 874-877.

Okodua, M. A., Nwobu, G. O., Tatfeng, Y. M., Ongey, J. Y., & Agwu, E. (2004). Incidence of HIV-related pulmonary tuberculosis in Edo State, Nigeria. Shiraz E-Medical Journal, 5(1), 10–15.

Onipede, A. O., Idigbe, O., Ako-Nai, A. K., Omojola, O., Oyelese, A. O., Aboderin, A. O., Komolafe, A. O., & Wemambu, S. N. C. (1999). Seroprevalence of HIV antibodies in TB patients in Ile-Ife. East African Medical Journal, 76(3), 127-132.

Rothenberg, R. B., Scarlett, M., del Rio, C., Reznik, D., & O'Daniels, C. (1998). Oral transmission of HIV. AIDS, 12(16), 2095–2105.

Salami, A. K., & Katibi, I. A. (2006). Human immunodeficiency virus associated tuberculosis: Pattern and trend in the University of Ilorin Teaching Hospital. African Journal of Medical Sciences, 2, 12-15.

Silvero, A. M., Acevedo-Gadea, C. R., & Pantanowitz, L. (2009). Unsuspected parvovirus B19 infection in a person with AIDS. The AIDS Reader, 19(6), 121-124.

World Health Organization. (2006). Global tuberculosis control – Surveillance, planning, financing. WHO Report 2006.

World Health Organization. (2007). Male circumcision: Global trends and determinants of prevalence, safety and acceptability, 1-30.

World Health Organization. (2008). WHO Report 2008: Global tuberculosis control. Retrieved from http://www.who.int/tb/publications/global_report/2008/annex_3/en/index.html

World Health Organization. (2010). Tuberculosis fact sheet N°104. Retrieved from http://www.who.int/mediacentre/factsheets/fs104/en/index.html

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Published

2024-06-02

How to Cite

Obeka, Maxwell Okoroafor, & Adeniran Adeniyi Ayobami. (2024). Assessment of Tuberculosis Treatment Strategies in HIV Patients: A Comparative Study of Two Healthcare Facilities in Oyo State, Nigeria. International Journal of Integrative and Modern Medicine, 2(6), 265–275. Retrieved from https://medicaljournals.eu/index.php/IJIMM/article/view/548