Modern Scientific Concepts and Clinical Consequences of LONG COVID Syndrome, Especially In Relation to its Impact on Cardiovascular Diseases

Modern scientific data confirm that post-covid syndrome (LONG COVID) has a significant impact on the cardiovascular system, especially increasing the risk of hypertension, myocarditis, thrombosis, and endothelial dysfunction. Studies show that patients who have had COVID-19 exhibit renin-angiotensin-aldosterone system (RAAS) regulation disorders, which can contribute to the development of hypertension even in previously healthy individuals. Also, persistent changes in the expression of microRNA involved in inflammatory and fibrotic processes have been identified, which can accelerate the progression of cardiovascular diseases [1]. Additionally, autonomic nervous system dysfunction, accompanied by increased sympathetic nervous system activity, can also play a role in post-covid hypertension. Clinical consequences include an increased risk of stroke, heart attack, and heart failure.

In therapeutic practice, it is recommended to pay attention to long-term monitoring of blood pressure, correction of inflammatory processes, and maintenance of endothelial health [2].