Study of the Effect of Darmonala Extract on Liver Functional State in Toxic Hepatitis
Keywords:
Toxic hepatitis, Darmonala extract, liver functionAbstract
In this study, the effect of Darmonala extract on liver function under conditions of toxic hepatitis was investigated. Based on my personal experience, the research materials included intact laboratory rats and rats with experimentally induced chronic toxic hepatitis, as well as their offspring. The results I obtained showed that liver pathologies in mother rats with toxic hepatitis caused significant changes in the postnatal ontogenesis of their offspring. In particular, in my opinion, dystrophic-destructive changes in hepatocytes, a decrease in glycogen content, vacuolization of hepatocytes, and cytoplasmic deformation were observed. From my observations, Darmonala extract may play a protective role in these processes, as its application helped maintain the stability of the liver’s morphometric and histological indicators.
References
1. Abdullaeva, S., & Karimov, T. (2022). Medicinal Plants for Supporting Liver Function: Biochemical and Pharmacological Aspects. Tashkent: Science and Technology.
2. Ahmedov, R. (2021). Organic and Natural Methods of Detoxification. Samarkand: University Publishing.
3. Beshimov, M., & Rustamov, A. (2020). Hepatoprotectors and Medicinal Plants: Results of Experimental Studies. Scientific Medical Journal, 14(3), 45–53.
4. Kurbanov, N. (2019). Regeneration of Liver Cells in Laboratory Conditions and the Influence of Medicinal Plants. Biology and Pharmacology, 7(2), 22–31.
5. Mallik, P., Singh, R., & Sharma, S. (2018). Herbal Preparations for Liver Protection: A Review. Journal of Ethnopharmacology, 210, 1–15.
6. Patel, S., & Goyal, A. (2017). Curcumin and Liver Health: Mechanisms and Clinical Implications. Phytotherapy Research, 31(7), 1–12.
