Evaluation of Bone Mineral Density Change in Patients with Axial Spondyloarthritis

Abstract

The aim of the study was to study the changes in bone mineral density (BMD) in patients with axial spondylarthritis (aksSpA).

Material and methods. For 4 years (2019-2023), 252 patients who applied for medical advice to the department of the specialized arthrological outpatient treatment course of the multidisciplinary clinic of the Tashkent Medical Academy were studied. In all patients, bone mineral density (BMD) was determined by dual-energy X-ray absorptiometry in g/cm2 and Z-criterion using a stationary dual-energy Lunar Prodigi Primo (USA, General Electric HEALTH CARE) bone X-ray densitometer.

Results. In patients with axSpA in both the lumbar spine and femoral neck, BMD was statically significantly reduced compared with the control group. In patients with axSpA, normal BMD indicators were detected in 38.9% of cases, osteopenic syndrome (OPS) – in 147 (58.3%) patients: osteopenia (OPe) – in 61 (24.2%) and osteoporosis (OP) – in 86 (34.1%), and in the control group normal BMD indicators were detected in 68.6% of cases, OPS in 22 (31.4%): OPe – in 17 (22.8%) and OP – in 6 (8.6%) subjects.