Autoimmune Thyroiditis - As Part of Multiorgan Autoimmune Syndrome(Literature Review)
Keywords:
autoimmune thyroid disease; autoimmune polyglandular syndromes; multiorgan autoimmune syndrome; chronic autoimmune thyroiditis; autoimmune diseasesAbstract
The 21st century has been declared the "century of autoimmune diseases", of which there are more than a hundred to date. The natural course of an autoimmune disease is characterized by progression from latent and subclinical stages to clinical and is associated with the presence of specific circulating autoantibodies. During the life of a person with one verified autoimmune disease, there is a high probability of sequential manifestation of other autoimmune pathologies. Every fourth patient with chronic autoimmune thyroiditis develops autoimmune non-thyroidal pathologies, and vice versa, chronic autoimmune thyroiditis is often found among people with non-thyroidal autoimmune diseases. Modern concepts of the pathogenetic mechanisms of development and progression of autoimmune diseases allow us to consider chronic autoimmune thyroiditis as a "signal pathology" in multiorgan autoimmune syndrome.
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