Vitamin K2 and its Influence on Bone Mineralization among Body Adults

vitamin k2 bone mineralization osteoporosis osteocalcin alkaline phosphatase

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June 30, 2025

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osteoporosis is a widespread metabolic bone disorder characterized by decreased bone mass and structural deterioration, leading to increased fragility and fracture risk. Nutritional factors, particularly vitamin k2, have emerged as critical in bone health due to their role in activating osteocalcin and regulating calcium homeostasis.

Objective: this study investigates the effects of vitamin k2 supplementation on bone mineralization among Iraqi adults, using clinical assessments

Methods: a randomized clinical study was conducted involving 103 participants aged 50–85 years. Statistical analysis was performed using SPSS. the period of study was 4 months

Results: vitamin k2 supplementation significantly increased serum calcium, alp, and osteocalcin levels (p < 0.05), BMD in the lumbar spine increased notably in the treatment group.

Conclusion: vitamin k2 enhances bone mineralization, supporting its role as a potential adjunct therapy for osteoporosis prevention and treatment, particularly in aging populations.

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