The Mechanism of Alcoholic Liver Damage
Keywords:
ADH, ALDH, ROS, Allogeneic hepatocytesAbstract
Liver diseases, especially acute toxic, ischemic and alcoholic liver damage, remain one of the main causes of liver failure. These diseases can lead to severe consequences, such as cirrhosis of the liver, liver failure, and require urgent medical intervention. Allogeneic hepatocytes, as a treatment method, open up new perspectives in restoring liver function, while it is poorly understood how this correction affects metabolic and immunological parameters in patients with acute liver damage.
References
1. Burnevich E.Z. Hepatic encephalopathy in cirrhosis of the liver [Text] /E.Z.Burnevich, T.N., M.S.Krasnova // Hepatological. forum. – 2018. – No. 2. –pp. 19-24.
2. Butorova L.I. Medicinal liver lesions [Text]: textbook.- methodical. manual / L.I.Butorova, A.V.Kalinin, A.F.Loginov. Moscow: Federal State University "NMHTS named after N.I. Pirogov", 2015. 65 p.
3. Vartanyan F.E. Tuberculosis: problems and scientific research in the countries of the world [Text] / F.E.Vartanyan, K.P.Shakhovsky // Problems of tuberculosis. 2002. No. 8. pp. 48-49.
4. Vasilenko Yu.K. The effect of pectoinulin and its combination with taurine on detoxifying activity of the liver [Text] / Y.K.Vasilenko [et al.] //Vestn. Russian University of Friendship of Peoples.- 2012. – No. 1. – pp. 22-26.-Ser. Medicine.
5. Vedennikova A.V. Genetic aspects of alcoholic liver disease. The results of the study [Text] / A.V.Vedennikova [et al.] // Hepatology today: tez.dokl. tenth Russian Conference– Moscow, 2005– p.57.
6. Vedrova N.N. Experience of using methadoxyl in the complex treatment of alcoholic liver damage [Text] / N.N. Vedrova, N.Yu. Gnezdilova // Narcologist.-2005.-No. 4. - pp. 24-26.
7. Vengerovsky A.I. Methodological guidelines for the study of hepatoprotective activity of pharmacological substances [Text] / A.I.Vengerovsky, I.V.Markova, A.S.Saratikov // Guidelines for the experimental (preclinical) study of new pharmacological substances / edited by V.P.Fisenko. – Moscow, 2000. – pp.228-231.
8. Vengerovsky A.I. Methodological guidelines for the study of hepatoprotective activity of pharmacological substances [Text] / A.I.Vengerovsky, I.V.Markova, A.S.Saratikov // Guidelines for the experimental (preclinical) study of new pharmacological substances / edited by R.U. Khabriev. Moscow, 2005. pp.683-691. 285
9. Verokhobina N.V. The place of Dibikor in the treatment of patients with type 2 diabetes mellitus and metabolic syndrome [Text] / N.V.Verokhobina, A.V.Kuznetsova // Pharmateca. - 2012. – No. 3. – pp.75-7
