Age-Related Variations in the Clinical Course and Management of Rhinosinusitis

In recent decades, substantial progress has been achieved in diagnosing and treating respiratory tract disorders, particularly various forms of sinusitis — a condition affecting over 20% of the global population. Advances in immunology, genetics, and molecular biology have significantly deepened our understanding of the mechanisms responsible for pathological tissue changes at the cellular level. The development of novel pharmacological agents and improved generations of antibiotics has enabled more effective control over a wide range of infectious pathogens.