Current Views about Ulcerative Colitis and its Impact on the Kidneys

Increasing interest in the problem of inflammatory bowel diseases (IBD) among medical practitioners and researchers is due to the variety of extraintestinal manifestations, including kidney pathology. In this area, tubulointerstitial nephritis, nephrolithiasis, glomerulonephritis, IgA and IgM nephropathies, and renal amyloidosis are distinguished. The mechanisms of development of tubulointerstitial nephritis in IBD remain the subject of debate. Some researchers view it as an extraintestinal manifestation of IBD related to its activity. It is noted that specific proteins found in the urine may indicate damage to the renal tubular apparatus, often associated with the activity of ulcerative colitis and Crohn's disease.