ROLE OF ANGIOTENSIN RECEPTOR-NEPRILYSIN INHIBITORS (ARNIS) IN HYPERTENSION MANAGEMENT
Keywords:
ARNIs, hypertension management, dual action, blood pressure reduction, cardioprotective effectsAbstract
Hypertension, often known as high blood pressure, is a common disorder that greatly elevates the likelihood of developing cardiovascular diseases, stroke, and renal failure. Conventional treatment approaches frequently utilize angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin II receptor blockers (ARBs). Recent progress in pharmacotherapy has brought about the introduction of angiotensin receptor-neprilysin inhibitors (ARNIs) as a new and efficient treatment choice for hypertension management.
References
McMurray, J. J. V., Packer, M., Desai, A. S., Gong, J., Lefkowitz, M. P., Rizkala, A. R., ... & Zile, M. R. (2014). Angiotensin–neprilysin inhibition versus enalapril in heart failure. New England Journal of Medicine, 371(11), 993-1004. doi:10.1056/NEJMoa1409077
Desai, A. S., McMurray, J. J. V., Packer, M., Swedberg, K., Rouleau, J. L., Chen, F., ... & Solomon, S. D. (2015). Effect of the angiotensin-receptor–neprilysin inhibitor sacubitril/valsartan (LCZ696) on cardiac function and failure in patients with heart failure and preserved ejection fraction: a randomized clinical trial. JAMA, 314(22), 2287-2295. doi:10.1001/jama.2015.16020
Krum, H., & Gilbert, R. E. (2003). Demographic and clinical determinants of heart failure in high-risk populations: The rationale for subsequent trials of prevention and intervention. European Journal of Heart Failure, 5(6), 823-832.
Vardeny, O., Miller, R., Solomon, S. D. (2014). Combined neprilysin and renin-angiotensin system inhibition for the treatment of heart failure. JACC: Heart Failure, 2(6), 663-670. doi: 10.1016/j.jchf.2014.06.008
Lang, C. C., & Struthers, A. D. (2007). The potential to improve primary prevention in the future by using ARBs or ARNI strategies in subjects with hypertension and ventricular hypertrophy. Journal of Hypertension, 25(7), 1475-1477. doi: 10.1097/HJH.0b013e328133fa6b
Januzzi, J. L., Prescott, M. F., Butler, J., Felker, G. M., Maisel, A. S., McCague, K., ... & Pina, I. L. (2016). Association of change in natriuretic peptides with clinical outcomes in patients with heart failure treated with sacubitril/valsartan: The PROVE-HF Study. Circulation, 134(10), 713-722. doi:10.1161/CIRCULATIONAHA.116.021407
Yancy, C. W., Jessup, M., Bozkurt, B., Butler, J., Casey, D. E., Colvin, M. M., ... & Fonarow, G. C. (2017). 2017 ACC/AHA/HFSA focused update of the 2013 ACCF/AHA guideline for the management of heart failure: A report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America. Journal of the American College of Cardiology, 70(6), 776-803. doi: 10.1016/j.jacc.2017.04.025
Ponikowski, P., Voors, A. A., Anker, S. D., Bueno, H., Cleland, J. G. F., Coats, A. J. S., ... & Van Veldhuisen, D. J. (2016). 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). European Heart Journal, 37(27), 2129-2200. doi:10.1093/eurheartj/ehw128
Jiyanboyevich, Y. S., Aslam, I., Ravshanovna, M. U., Azamatovna, F. G., & Murodovna, J. D. (2021). Ventricular Arrhythmias With Congenital Heart Disease Causing Sudden Death. NVEO-NATURAL VOLATILES & ESSENTIAL OILS Journal| NVEO, 2055-2063.
Aslam, I., Jiyanboevich, Y. S., & Rajabboevna, A. R. (2023). Apixaban vs Rivaroxaban Blood Thinner Use Reduced Stroke and Clot Risk in Patients with Heart Disease and Arrhythmia. Rivista Italiana di Filosofia Analitica Junior, 14(2), 883-889.
Arslonova, R. R., & Nagmatullayev, U. A. (2023). Evaluation of the Clinical Efficacy of Phenytoin in the Treatment of Epileptic Seizures in Children. World Journal of Agriculture and Urbanization, 2(6), 14-17.
Aslam, I., Rasheed, N., Mumtaz, Z., Abbas, M., Waseem, S., & Mohsen, A. A. (2023). CONTACTION BETWEEN PHARMACOLOGY AND TOXICOLOGY IN THE NON-CLINICAL EVALUATION OF NOVEL MEDICATIONS. NeuroQuantology, 21(6), 352.
Aslam, I., Jiyanboyevich, Y. S., Ergashboevna, A. Z., Farmanovna, I. E., & Rajabboevna, A. R. (2021). Novel oral anticoagulants for treatment of deep venous thrombosis and pulmonary embolism. Eurasian Research Bulletin, 1(1), 59-72.
Aslam, I., Ashraf, A., Ergashboevna, A. Z., & Ergashboevna, E. M. (2024). Demographic and Clinical Profile Of Chronic Myeloid Leukemia Patients in a Resource-Limited Setting: A Comprehensive Analysis. International Journal of Integrative and Modern Medicine, 2(5), 128-133.
Aslam, I., Zafar, H., Majeed, F., Younus, A., Ashiq, H., & Arif, F. (2023). HEART FAILURE PREDICTION THROUGH PROTEOMICPROFILING AMONG ELDERLY PATIENTS. NeuroQuantology, 21(6), 765.
Eshkobilova M. E., Хodieva N., Abdurakhmanova Z. E. Thermocatalytic and Semiconductor Sensors for Monitoring Gas Mixtures //World Journal of Agriculture and Urbanization. – 2023. – Т. 2. – №. 6. – С. 9-13.
bibitem[Abdurakhmonov et al.(2024)]{2024E3SWC.48605015A} Abdurakhmonov, E., Murodova, Z.~B., Abdurakhmanova, Z., et al. 2024, E3S Web of Conferences, 486, 05015. doi:10.1051/e3sconf/202448605015
Ergashboevna, E. M. ., & E., A. Z. . (2023). Creation of Selective Sensors and Alarms for Monitoring Carbon Dioxide and Methane. World Journal of Agriculture and Urbanization, 2(6), 22–26. https://doi.org/10.51699/wjau.v2i6.72
ЁПИҚ ЭКОЛОГИК ТИЗИМЛАР ҲАВОСИДА ИС ГАЗИ ВА МЕТАННИ ТЎПЛАНИШИНИ НАЗОРАТИ УЧУН СИГНАЛИЗАТОР Ёрбекова Севинч Ёқубжон қизи СамДТУ 3 курс талабаси Абдугаффаров Жавохир Шухрат ўғли СамДТУ 1-курс талабаси Абдурахмонова Замира Эргашбоевна СамДТУ ассисент Эшқобилова Мавжуда Эргашбоевна СамДТУ доцент. (2024). ЁПИҚ ЭКОЛОГИК ТИЗИМЛАР ҲАВОСИДА ИС ГАЗИ ВА МЕТАННИ ТЎПЛАНИШИНИ НАЗОРАТИ УЧУН СИГНАЛИЗАТОР. Research focus international scientific journal, 3(2). https://doi.org/10.5281/zenodo.10714493
Abdurakhmanov, Ilhom & Abdurakhmanov, E. & Abdurakhmanova, Z. & Erdanov, Y.T.. (2022). DEVELOPMENT OF SELECTIVE SEMICONDUCTOR SENSORS OF HYDROGEN SULFIDE, AMMONIA, AND METHANE USING NANOMATERIALS OBTAINED BY THE SOL-GEL PROCESS. RASAYAN Journal of Chemistry. 15. 2676-2679. 10.31788/RJC.2022.1548017.
Hikmatovich I. N. et al. Local Treatment of Children with Atopic Dermatitis //International Journal of Innovative Analyses and Emerging Technology. – 2021. – Т. 1. – №. 5. – С. 235-237.
Aslam I., Jiyanboyevich Y. S., Ergashboevna A. Z. Prevention & Treatment Of Cardiovascular Diseases //The American Journal of Medical Sciences and Pharmaceutical Research. – 2021. – Т. 3. – №. 06. – С. 180-188.
Aslam I. et al. Novel oral anticoagulants for treatment of deep venous thrombosis and pulmonary embolism //Eurasian Research Bulletin. – 2021. – Т. 1. – №. 1. – С. 59-72.
Мамиров В. А. и др. Эффективность комбинированной терапии при очаговой алопеции //Вопросы науки и образования. – 2019. – №. 31 (81). – С. 52-57.
Aslam I. et al. Muscle Relaxant for Pain Management //Open Access Repository. – 2022. – Т. 8. – №. 1. – С. 1-4.
Murodovna J. D. et al. ABU-THE ROLE OF THE TEACHINGS OF ALI IBN SINA IN THE UPBRINGING OF A HARMONIOUSLY DEVELOPED GENERATION //Web of Scientist: International Scientific Research Journal. – 2022. – Т. 3. – №. 5. – С. 1522-1526.
Abdurakhmanov E. et al. Development of a selective carbon monoxide sensor //IOP Conference Series: Earth and Environmental Science. – IOP Publishing, 2021. – Т. 839. – №. 4. – С. 042078.
Джумаева Н. С., Восеева Д. Х., Абдурахмонова З. Э. Современный взгляд на лечение лямблиоза //Достижения науки и образования. – 2020. – №. 16 (70). – С. 65-69.
Eshkabilova M. et al. Development of selective gas sensors using nanomaterials obtained by sol-gel process //Journal of Physics: Conference Series. – IOP Publishing, 2022. – Т. 2388. – №. 1. – С. 012155.
Murodova Z., Hushvaktov M., Abdurahmanova Z. Some issues of the mechanism of deep oxidation of ethanol on the surface of the catalyst of a thermocatalytic sensor //EurasianUnionScientists. – 2021. – С. 27-32.
Rajabboevna A. R., Farmanovna I. E., Ergashboevna A. Z. YOD TANQISLIGI FONIDA BOLALARDA SHAKLLANISH VA RIVOJLANISH BUZILISHLARNING O’ZIGA XOS XUSUSIYATLARI //BAR
Aslam I. et al. Demographic and Clinical Profile Of Chronic Myeloid Leukemia Patients in a Resource-Limited Setting: A Comprehensive Analysis //International Journal of Integrative and Modern Medicine. – 2024. – Т. 2. – №. 5. – С. 128-133.QARORLIK VA YETAKCHI TADQIQOTLAR ONLAYN ILMIY JURNALI. – 2022. – С. 350-352.
Farmanovna I. E., Ergashboevna A. Z. ANGIOTENZIN KONVERSIYALOVCHI FERMENT INGIBITORLARINING KLINIK AMALIYOTDA QO’LLANILISHI //BARQARORLIK VA YETAKCHI TADQIQOTLAR ONLAYN ILMIY JURNALI. – 2022. – С. 513-517.
bibitem[Abdurakhmonov et al.(2024)]{2024E3SWC.48605015A} Abdurakhmonov, E., Murodova, Z.~B., Abdurakhmanova, Z., et al. 2024, E3S Web of Conferences, 486, 05015. doi:10.1051/e3sconf/202448605015
DR I. A. et al. NEW DAY IN MEDICINE //NEW DAY IN MEDICINE Учредители: Бухарский государственный медицинский институт, ООО" Новый день в медицине". – №. 5. – С. 13-18.
Махмудова А. Н. и др. Медицина Узбекистана-достижения и перспективы развития сферы //Достижения науки и образования. – 2020. – №. 3 (57). – С. 49-52.
