Study Some Parameters in Patients with Asthenooligozoospermia
Keywords:
Asthenooligozoospermia, vitamin D, testosterone hormone and IL17Abstract
Asthenooligozoospermia is a form of male infertility, which affects the quality of sperm motility and leads to decreased fertility rates, Current diagnostic and therapeutic methods fail to solve most infertility problems. Samples were collected from the Infertility Center at Al-Sadr Teaching Hospital, the results showed that infertile individuals had significantly higher levels of interleukin 17. The results indicated that the amount of testosterone and vitamin D decreased significantly. The parameters had a direct correlation with testosterone and vitamin D. The results showed that interleukin 17 and the parameters had an inverse correlation. semen as well as with testosterone. It can be said that the negative effect of the vitamin D has a negative impact on men in terms of fertility, due to low levels of testosterone, weak immunity or changes in sperm quality, which may lead to other problems.
References
Al-Msaid, H. L., & Al-Sallami, A. S. (2018). Study the level of cytokine in unexplained and idiopathic infertile men. Journal of Pharmaceutical Sciences and Research, 10(4), 808-811.
Zańko, A., Martynowicz, I., Citko, A., Konopka, P., Paszko, A., Pawłowski, M., ... & Milewski, R. (2024). The Influence of Lifestyle on Male Fertility in the Context of Insulin Resistance—Identification of Factors That Influence Semen Quality. Journal of Clinical Medicine, 13(10), 2797.
AL-Msaid, H. L., Waleed, A. H., & AL-Sallami, A. S. (2019). Relationship Between Hyperviscosity and Sex Hormone in Azoospermia and Oligozoospermia Patients Compares with The Control Group. Int J Pharm Qual Assur, 10(4), 637-9.
Abedpoor, N., Taghian, F., & Hajibabaie, F. (2024). Exploring the dynamics of exercise intensity on male fertility and reproductive health: advancements and implications for fertility research. Frontiers in Reproductive Health, 6, 1423916.
Hayder, L. F., & Alaauldeen, S. M. (2018). Study of Catsper1 Protein Levels in Unexplained and Idiopathic Infertile Men. International Journal of Pharmaceutical Quality Assurance, 9(2), 195-198.
AL-Msaid, H. L., Khalfa, H. M., Rashid, A. A., & Hussain, N. N. M. (2024). Relationship between Sperm DNA Fragmentation and Interleukin 17 in Patients with Leukocytospermia. Journal of Bioscience and Applied Research, 10(4), 809-815.
Andrabi, S. W., Ara, A., Saharan, A., Jaffar, M., Gugnani, N., & Esteves, S. C. (2024). Sperm DNA Fragmentation: Causes, evaluation and management in male infertility. JBRA Assisted Reproduction, 28(2), 306.
Vahedi Raad, M., Firouzabadi, A. M., Tofighi Niaki, M., Henkel, R., & Fesahat, F. (2024). The impact of mitochondrial impairments on sperm function and male fertility: a systematic review. Reproductive Biology and Endocrinology, 22(1), 83.
Sharpe, R. M. (2024). Endocrine disruption and male reproductive disorders: unanswered questions. Human Reproduction, 39(9), 1879-1888.
Parvez, K. F., & Hussain, S. S. (2025). The Role of Industrial Chemicals and Occupational Hazards in Male Infertility: A Comprehensive Review. Metallurgical and Materials Engineering, 31(1), 52-65.
Xue, S., Li, X., Zhou, S., Zhang, J., Sun, K., Peng, X., ... & Yan, W. (2024). Effects and mechanisms of endocrine disruptor bisphenol AF on male reproductive health: A mini review. Ecotoxicology and Environmental Safety, 276, 116300.
Sadek, K. M., Khalifa, N. E., Alshial, E. E., Abdelnour, S. A., Mohamed, A. A. R., & Noreldin, A. E. (2024). Potential hazards of bisphenol A on the male reproductive system: Induction of programmed cell death in testicular cells. Journal of Biochemical and Molecular Toxicology, 38(9), e23844.
Boisen, I. M., Holt, R., Kooij, I., Yahyavi, S. K., Mortensen, L. J., & Jensen, M. B. (2024). Vitamin D, reproductive endocrinology, and male reproductive organ function in health and disease. In Feldman and Pike's Vitamin D (pp. 889-924). Academic Press.
Abu-Zaid, A., Saleh, S. A., Adly, H. M., Baradwan, S., Alharran, A. M., Alhatm, M., ... & Alomar, O. (2024). The Impact of Vitamin D on Androgens and Anabolic Steroids among Adult Males: A Meta-Analytic Review. Diseases, 12(10), 228.
Wall-Gremstrup, G., Holt, R., Yahyavi, S. K., Jorsal, M. J., Juul, A., Jørgensen, N., & Blomberg Jensen, M. (2024). High-dose vitamin D3 supplementation shows no beneficial effects on white blood cell counts, acute phase reactants, or frequency of respiratory infections. Respiratory Research, 25(1), 11.
Holt, R., Yahyavi, S. K., Kooij, I., Poulsen, N. N., Juul, A., Jørgensen, N., & Blomberg Jensen, M. (2024). Effects of vitamin D on sex steroids, luteinizing hormone, and testosterone to luteinizing hormone ratio in 307 infertile men. Andrology, 12(3), 553-560.
Allosso, F., Digitale, S. L., Grande, G., Errico, M., Di, L. C., Navarra, R., & Pasquali, D. (2024, May). Vitamin d and reproduction in hereditary vitamin d resistant rickets. what we can learn from an in vivo model. In Endocrine Abstracts (Vol. 99). Bioscientifica.
Paskeh, M. D. A., Babaei, N., Hashemi, M., Doosti, A., Hushmandi, K., Entezari, M., & Samarghandian, S. (2024). The protective impact of curcumin, vitamin D and E along with manganese oxide and Iron (III) oxide nanoparticles in rats with scrotal hyperthermia: Role of apoptotic genes, miRNA and circRNA. Journal of Trace Elements in Medicine and Biology, 81, 127320.
Porubska, B., Plevakova, M., Fikarova, N., Vasek, D., Somova, V., Sanovec, O., ... & Krulova, M. (2024). Therapeutic potential of Sertoli cells in vivo: alleviation of acute inflammation and improvement of sperm quality. Stem Cell Research & Therapy, 15(1), 282.
Carrageta, D. F., Pereira, S. C., Ferreira, R., Monteiro, M. P., Oliveira, P. F., & Alves, M. G. (2024). Signatures of metabolic diseases on spermatogenesis and testicular metabolism. Nature Reviews Urology, 1-18.
Wang, L. H., Zheng, L., Jiang, H., & Jiang, T. (2024). Research advances in inflammation and oxidative stress in varicocele-induced male infertility: a narrative review. Asian Journal of Andrology, 10-4103.
Rotimi, D. E., Ojo, O. A., & Adeyemi, O. S. (2024). Atrazine exposure caused oxidative stress in male rats and inhibited brain‐pituitary‐testicular functions. Journal of Biochemical and Molecular Toxicology, 38(1), e23579.
Li, L., Lin, W., Wang, Z., Huang, R., Xia, H., Li, Z., ... & Yang, Y. (2024). Hormone Regulation in Testicular Development and Function. International Journal of Molecular Sciences, 25(11), 5805.
Andrabi, S. W., Ara, A., Saharan, A., Jaffar, M., Gugnani, N., & Esteves, S. C. (2024). Sperm DNA Fragmentation: Causes, evaluation and management in male infertility. JBRA Assisted Reproduction, 28(2), 306.
Lira, F. T., Campos, L. R., Roque, M., & Esteves, S. C. (2024). From pathophysiology to practice: addressing oxidative stress and sperm DNA fragmentation in Varicocele-affected subfertile men. International braz j urol, 50(5), 530-560.
