The Importance of Insulin-Like Growth Factor and the Relevance of its Research
Keywords:
IGF-I, IGF-II, growth hormons, growth factors, replacement therapyAbstract
It is known that growth hormone is a pleiotropic hormone that causes the growth of all organs by coordinating many physiological processes, including its effect on the nervous system, bones, muscles and fat. Metabolically, growth hormone promotes anabolic action in most tissues except adipose tissue, and its catabolic effect leads to the breakdown of accumulated triglycerides into free fatty acids. On the other hand, insulin-like growth hormone is a hormone that serves to indirectly exercise its activity by stimulating this aforementioned growth hormone. Due to its diverse activity and effectiveness, it encourages consideration of the possibility of its use for diagnostic and therapeutic purposes. In many pathologies of the nervous system, cardiovascular and other organs, its amount may shift to one degree or another, and in this regard, the possibilities of inclusion in diagnostic measures are being considered, based on the magnitude of this shift. However, when treating with insulin-like growth factor, it is very important to regulate its amount, since an overdose when using it or vice versa can lead to a violation of hormonal interaction in the body. This leads to various serious disorders in the body. For this reason, substitution or substitution therapy also requires strict caution when using it when considering the prospects of its use in certain oncological diseases. However, given that the level of IGF-1 expression varies depending on a number of clinical conditions, constant maintenance of IGF-I levels within the normal range allows you to avoid side effects caused by its use, as well as to obtain important promising treatment results.
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