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Assessment of Immune Status and Risk of Oral Candidiasis Development in Patients With Leukemia

Vol. 3 No. 11 (2025): International Journal of Integrative and Modern Medicine:
Published : Nov 29, 2025

Orifkhujayeva Mekhriniso Valijonovna (1), Norova Mavjuda Baxodurovna (2)

(1) Basic Doctoral Student (PhD Candidate) at Bukhara State Medical Institute, Uzbekistan
(2) Associate Professor, Department of Therapeutic Dentistry, Bukhara State Medical Institute, DSc, Uzbekistan
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Abstract:

Oral candidiasis is a common opportunistic infection in patients with leukemia due to compromised immune function. This review aims to evaluate the relationship between immune status and the risk of developing oral candidiasis in these patients. Neutropenia, impaired cellular immunity, and disruption of oral microbiota increase susceptibility to Candida colonization and infection. Understanding these mechanisms is essential for early diagnosis, effective prevention, and optimal therapeutic interventions.

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