Clinical and Functional Characteristics of Knee Joint Damage in Patients with Gonarthrosis in Combination with Metabolic Syndrome

Diseases of the musculoskeletal system and connective tissue are considered worldwide as one of the most common pathologies in modern society, leading to temporary and permanent disability. The most common diseases of the musculoskeletal system are degenerative lesions that affect both the structures of the joint itself (hyaline cartilage, subchondral bone) and periarticular structures (entheses, tendons, bursias). The most common form of joint damage is osteoarthritis, caused by an imbalance in the processes of repair and degradation in the articular cartilage. * Osteoarthritis causes a deterioration in the quality of life, leading to early disability of patients, and occupies a leading position (60%) among rheumatic diseases. In the structure of osteoarthritis, a special place belongs to the lesion of the joints of the lower extremities, in particular the knee joints, which carry the main weight load. According to literature data, 80-97% of the population over the age of 60 suffers from osteoarthritis. Osteoarthritis of the knee joints attracts special attention due to its significant prevalence, often its progressive course, disability of patients, as well as severe pain syndrome, which significantly reduces physical activity and quality of life of patients.