The Frequency of Cardiovascular Events in Patients of Working Age with Unfavorable Remodeling of the Left Ventricle after Myocardial Infarction

In this scientific work, the frequency of cardiovascular events in patients of working age with unfavorable remodeling of the left ventricle after myocardial infarction was analyzed. The study included 130 patients with STEMI (age 51.2±18.8 years) hospitalized in the departments of acute coronary syndrome and coronary heart disease and cardiac resuscitation of the Samarkand regional branch of the Republican Specialized Scientific and Practical Medical Center of Cardiology (SRF RSNPMC) in the first 24-96 hours from the onset of the disease. A prerequisite was the presence of hemodynamically significant stenosis of only one coronary artery according to the results of coronary angiography. Initially, on days 7-9 from the onset of the disease and after 24 weeks of follow-up, patients underwent standard echocardiography to determine the index of final diastolic volume (iCDO), the index of final systolic volume (ICso). After 24 weeks, the patients were divided into two groups. Group 1 included 68 patients with unfavorable LV remodeling (iCDO increase >20% and/or ICso>15%). Group 2 consisted of 62 patients without echocardiographic signs of cardiac remodeling. The development of unfavorable left ventricular remodeling after STEMI is associated with an 8.5-fold increase in the risk of cardiovascular events within 48 weeks after the index event.