Properties of Special Biomarkers in Immunological Studies of Systemic Scleroderma

Babamuradova Zarrina Bakhtiyarovna; Kuchkarova Shirina Alisherovna

Authors

Babamuradova Zarrina Bakhtiyarovna DSc, Associate Professor, Samarkand State Medical University, Uzbekistan
Kuchkarova Shirina Alisherovna Student group 425, Samarkand State Medical University, Uzbekistan

Vol. 3 No. 1 (2025): International Journal of Alternative and Contemporary Therapy

Articles

January 30, 2025

Scleroderma is a connective tissue disease characterized by damage to small and large vessels, inflammation, autoimmune disease, and tissue remodeling. This article analyzes the properties of the Siglec-1 biomarker in the immunological processes of systemic scleroderma. Siglec-1 is a type of lectin that binds to sialic acids, which plays an important role in the immune system and inflammatory processes. In systemic scleroderma, cells that highly express this biomarker, macrophages and dendritic cells, are important in controlling the inflammatory and fibrotic processes in the development of the disease. The diagnostic and prognostic properties of Siglec-1 help in identifying and predicting the early stages of the disease. Also, the therapeutic potential of Siglec-1 opens up the possibility of developing new treatments to modulate autoimmune inflammation in systemic scleroderma and prevent the development of fibrosis.

Bakhtiyarovna, B. Z., & Alisherovna, K. S. (2025). Properties of Special Biomarkers in Immunological Studies of Systemic Scleroderma. International Journal of Alternative and Contemporary Therapy, 3(1), 98–105. Retrieved from https://medicaljournals.eu/index.php/IJACT/article/view/1500

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Journal title	International Journal of Alternative and Contemporary Therapy
Initials	Int.Jour.Int.Mod.Med
Frequency	12 issues per year
Prefix DOI	10.xxxxx
Online ISSN	XXXX-XXXX
Editor In Chief	Jaung Geng Lin []
Publisher	Medical Journals Press

International Journal of Alternative and Contemporary Therapy

Properties of Special Biomarkers in Immunological Studies of Systemic Scleroderma

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