Modern View on the Factors of Inflammation in Peri-Implant Tissues and Methods for Its Prevention
Keywords:
Peri-implant tissues, inflammation, dental implants, prevention, bacterial colonization, osseointegrationAbstract
This article presents a review of current studies devoted to the factors influencing the development of inflammatory processes in peri-implant tissues, as well as methods for their prevention. The key etiological factors considered include bacterial colonization, characteristics of the immune response, bone tissue quality, and the influence of systemic diseases. Particular attention is paid to the role of the quality of the implant treatment protocol, the materials and design of implants, as well as the condition of the surrounding soft tissues. Modern preventive strategies are analyzed, including improvement of oral hygiene, the use of antimicrobial coatings, correction of systemic risk factors, and refinement of surgical techniques. The paper emphasizes the need for a comprehensive approach to preventing inflammatory complications, which is an important prerequisite for successful osseointegration and the long-term durability of dental implants.
References
[1] D. M. Ehrenfest, T. Bielecki, A. Mishra et al., “In search of a consensus terminology in the field of platelet concentrates for surgical use: PRP, PRF, fibrin gel polymerization and leukocytes,” Current Pharmaceutical Biotechnology, no. 7 (13), pp. 132–133, 2012.
[2] M. Esposito, M. G. Grusovin, and H. V. Worthington, “Treatment of periimplantitis: what interventions are effective? A Cochrane systematic review,” Oral Implantology, no. 5, pp. 21–41, 2012.
[3] S. Ghanaati et al., “Advanced platelet-rich fibrin: a new concept for cell-based tissue engineering by means of inflammatory cells,” Journal of Oral Implantology, vol. 40, no. 6, pp. 679–689, 2014.
[4] T. Koyanagi, M. Sakamoto, Y. Takeuchi, and N. Maruyama, “Comprehensive microbiological findings in peri-implantitis and periodontitis,” Journal of Clinical Periodontology, vol. 40, pp. 218–226, 2013.
[5] C. Mesmer, A. Forster, M. Antal, and K. Nagy, “Clinical, microbiological and immunological findings in peri-implantitis patients,” Fogorv Sz, vol. 105, pp. 59–64, 2012.
[6] S. Verardi, M. Quaranta, and S. Bordin, “Peri-implantitis fibroblasts respond to host immune factor C1q,” Journal of Periodontology, vol. 46, pp. 134–140, 2011.
[7] Y. Vered, A. Zini, and J. Mann, “Teeth and implant environments: clinical health indices and microbiological parameters,” Quintessence International, vol. 42, pp. 339–344, 2011.
[8] G. Vivek, K. B. Vivek, and G. P. Singh et al., “Regenerative potential of platelet rich fibrin in dentistry: literature review,” Asian Journal of Oral Health & Allied Sciences, vol. 1, no. 1, pp. 22–28, 2011.
[9] A. A. Gudaryan and S. V. Shirinkin, “Comprehensive treatment of dental mucositis,” The Scientific Heritage, no. 6 (6), pp. 22–27, 2016.
[10] A. A. Gudaryan and S. V. Shirinkin, “Comprehensive treatment of dental periimplantitis,” Sciences of Europe, no. 9 (9), pp. 38–44, 2016.
[11] A. A. Gudaryan, N. G. Idashkina, and S. V. Shirinkin, “Comparative effectiveness of polymylactic acid and collagen membranes in periimplantitis,” Medical Perspectives, vol. 19, no. 1, pp. 91–96, 2014.
[12] L. E. Leonova, A. S. Sutorikhina, G. A. Pavlova, and A. V. Popov, “Dynamics of hygienic condition at surgical interventions,” Social Medicine, no. 6 (31), pp. 87–90, 2014.
[13] I. S. Mashchenko, A. A. Gudaryan, and S. V. Shirinkin, “Direct implantation with bone augmentation and immediate load,” Visknik Stomatologicheskiy, no. 3, pp. 65–70, 2014.
[14] N. Yu. Perova, E. L. Vinichenko, and N. A. Bondarenko, “Immunotropic effect of Lycopid in periodontal treatment,” International Journal of Applied and Fundamental Research, no. 3–4, pp. 639–642, 2015.
[15] S. V. Shirinkin, “Comprehensive treatment of dental mucositis,” Modern Dentistry, no. 5, pp. 75–79, 2015.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 International Journal of Alternative and Contemporary Therapy

This work is licensed under a Creative Commons Attribution 4.0 International License.