The Importance of Functional Renal Impairments in Patients with Myocardial Infarction and Type 2 Diabetes Mellitus

myocardial infarction type 2 diabetes mellitus renal impairment kidney dysfunction acute kidney injury nephropathy diabetic nephropathy

Authors

  • Muminov Sherzod Uktamovich Head of the Department of Toxicology and ECD of the Samarkand branch of the Republican Scientific Center for Emergency Medical Care
  • Kenzhamuratova Klara Saribaevna Doctor of the toxicology and ECD department of the Samarkand branch of the Republican scientific center of emergency medical care
  • Abdulloeva Maftuna Dilshodovna Assistant of the Department of Internal Medicine and Cardiology No. 2 of the Samarkand State Medical University
March 18, 2025

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The aim of the study was to investigate the role of renal dysfunction in the aggravation of the clinical picture of acute myocardial infarction (MI) in patients with type 2 diabetes mellitus (DM 2). A total of 107 patients with acute myocardial infarction were examined: 38.3% women and 61.7% men. 65.4% of patients had type 2 diabetes mellitus. It was found that with type 2 DM, MI often develops in women of relatively older age (over 60 years), with a diabetes duration of more than 5 years, with a subcompensated or decompensated course of the disease. In type 2 DM, renal dysfunction is a risk factor for the development and aggravation of MI. Signs of nephropathy proteinuria, cylindrical filtration and a decrease in glomerular filtration below 80 ml/min are the background for the development of myocardial infarction. A decrease in SCF in patients with MI and type 2 diabetes below 60 ml/min can contribute to fatal outcomes.

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