Global Perspectives on Early Pregnancy Bleeding: Clinical Predictors, Hormonal Interventions, and Outcome Optimization

This research investigates clinical indicators together with hormonal variables that affect pregnancy results in women who face threatened abortion during early pregnancy stages at the Multidisciplinary Clinic of Samarkand State Medical University between 2023 and 2025 with 89 participating patients. The medical condition threatened abortion causes bleeding through the vagina in the early pregnancy phase when the cervix stays sealed with a living fetus inside. This obstetric issue exists globally yet different healthcare systems handle it differently because of unequal diagnostic skills along with treatment method variations and variable medical system resources. Because of this investigation all pregnant women who experienced first-trimester bleeding received both ultrasound evaluation and serum progesterone screenings. A system evaluated patients through hormone levels and bleeding severity before following their pregnancy outcomes to establish their variables' associations. The results of statistical analysis showed that women who had progesterone measurements below 10 ng/mL were more likely to experience miscarriage compared to those whose tests showed values above 20 ng/mL. The medical outcome of patients depended heavily on the extent of bleeding they experienced. The research both supports findings already presented in international literature and shows how practical progesterone screening combined with symptom-based management works when resources are limited. The study demonstrates both the requirement for national prenatal protocols to adopt hormonal diagnostics and the critical necessity of maternal healthcare interventions that start early. The research links clinical findings to worldwide proof to create implementable guidelines which help Uzbekistan and similar poor-resource settings lessen preventable pregnancy deaths and advance maternal wellness.