Rickets: Etiology, Pathogenesis and Clinical Course
Keywords:
Vitamin D deficiency, malnutrition, endocrine disorders, deficiency of phosphates and calcium salts, unfavorable environmental conditionsAbstract
Rickets is a disease in children characterized by softening and deformation of the bones, mainly caused by a deficiency of vitamin D and minerals, especially calcium and phosphorus. The article details the causes of rickets, its effects on growth, its symptoms, and risk groups. Poor nutrition, lack of sunlight, and environmental conditions can also be cited as causes of rickets. . The article provides knowledge and practical recommendations, especially for parents and pediatricians, necessary for protecting children's health.
References
1. B.Qorakho’dzhayev, I.T.Salomov, M.N.Abdullayeva - Clinical practice of children's diseases. 2006.
2. N.A. Rasulova, R.Kh.Sharipov – A new approach to the prevention and treatment of rickets. 2023.
3. T.A. Daminov, B.T.Khalmatova, U.R.Boboyeva – Children's diseases. 2012.
4. 4.U.K. Narzikulov, M.N.Bo’riyev, F.R.Umarkhodzhayev, U.S.H.Ro’zikulov, G’.M.Nazirkulov, U.M.Samadov – Practical skills in children's traumatology and orthopedics. 2015.
5. D.Kh. Mamatkulova, O.A.Sharipova – Rickets in children. 2022.
6. WHO. Guideline: Vitamin D supplementation in pregnant women. - Geneva: World Health Organization, 2012. - 36 p.
7. UNICEF. Global prevalence of vitamin D deficiency and rickets. - New York: UNICEF Publications, 2020. - 22
8. DeLuca, H.F. Overview of general physiological features and functions of vitamin D // Am. J. Clin. Nutr. - 2004. - Vol. 80(6). – P. 1689S–1696S.
9. Wagner, C.L., Greer, F.R. Prevention of rickets and vitamin D deficiency in infants, children, and adolescents // Pediatrics. - 2008. - Vol. 122(5). – P. 1142–1152.
10. Khripkova, A.G. Rickets and children: a modern view of the old problem // Voprosy sovremennoy pediatrii. - 2019. - T. 18, No. 2. – P. 73–78
