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Analysis of Postoperative Complications Following Perforated Duodenal Ulcer and the Impact of Clinical-Surgical Risk Factors

Vol. 3 No. 8 (2025): International Journal of Integrative and Modern Medicine:

Abdullaev Khakimjon Makhmudjonovich (1), Nuridinov Orifjon Tolipovich (2), Kholiqov Shavkatbek (3)

(1) Deputy Chief Surgeon, Namangan Regional Multidisciplinary Medical Center, Namangan, Uzbekistan, Uzbekistan
(2) Head of Department of Surgery No.1, Andijan State Medical Institute Clinic, Andijan, Uzbekistan, Uzbekistan
(3) Associate Professor, Department of Medical Biology and Histology, Andijan State Medical Institute, Andijan, Uzbekistan, Uzbekistan
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Abstract:

This study analyzes postoperative complications arising after surgical treatment of perforated duodenal ulcers — in particular, dumping syndrome and reflux gastritis — as well as the key clinical and surgical factors influencing their development. It was observed that complications were more frequently encountered in patients over the age of 50, those with large perforation sizes, and in cases where surgery was delayed. Additionally, the presence of underlying somatic diseases significantly increased the likelihood of postoperative complications. Risk assessment systems such as Boey, ASA, and PULP were found to have practical prognostic value in predicting adverse outcomes. The use of laparoscopic techniques, particularly the Graham patch method, was associated with a lower incidence of complications. The findings emphasize that individualized patient management, early detection, and continuous monitoring may contribute significantly to the prevention of postoperative complications.

References

1. Søreide K, Thorsen K, Harrison EM, Bingener J, Møller MH, Ohene-Yeboah M, Søreide JA. Perforated peptic ulcer. Lancet. 2015;386(10000):1288–1298. doi:10.1016/S0140-6736(15)00276-7.

2. Møller MH, Adamsen S, Wøjdemann M, Møller AM. Perforated peptic ulcer: how to improve outcome? Scand J Gastroenterol. 2009;44(1):15–22. doi:10.1080/00365520802321292.

3. Hamdi A, Ben Amar M, Zoghlami A, et al. Long-term outcome of surgically treated peptic ulcer. Review of a series of 419 patients operated for peptic ulcer. Ann Chir. 1991;45(6):490–496. [Article in French]

4. Boey J, Wong J, Ong GB. A prospective study of operative risk factors in perforated duodenal ulcers. Ann Surg. 1982;195(3):265–269. doi:10.1097/00000658-198203000-00005.

5. Lam PW, Lau HY, Lau WY. Laparoscopic repair of perforated duodenal ulcers: the "three-stitch" Graham patch technique. Surg Endosc. 2005;19(12):1627–1630. doi:10.1007/s00464-005-0259-3.

6. Arici C, Mesut E, Sayan A, et al. Analysis of risk factors predicting mortality and morbidity of peptic ulcer perforations. Int Surg. 2007;92(3):147–154.