Cervicitis (Endocervicitis): Diagnostic and Treatment Features With Emphasis on Uzbekistan

cervicitis endocervicitis Chlamydia trachomatis Neisseria gonorrhoeae Mycoplasma genitalium NAAT antimicrobial resistance Uzbekistan

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October 10, 2025

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Cervicitis is a common inflammatory condition of the uterine cervix, frequently asymptomatic, and associated with sexually transmitted infections (notably Chlamydia trachomatis and Neisseria gonorrhoeae), as well as Mycoplasma genitalium, Trichomonas vaginalis, and dysbiosis. This review synthesizes recent evidence for clinicians and researchers, detailing clinical presentation, diagnostic methods (speculum exam, microscopy, NAAT/PCR, culture), and treatment strategies adapted to antimicrobial resistance trends. Special emphasis is placed on Uzbekistan: the availability of laboratory diagnostics, empiric therapy patterns in urban versus rural settings, and antimicrobial stewardship. We discuss the shift from azithromycin to doxycycline-first strategies for non-pregnant adults, resistance-guided therapy for M. genitalium, partner management, and prevention. We outline implementation priorities for Uzbekistan’s health system: expanding NAAT access, integrating cervicitis into reproductive health programs, strengthening AMR surveillance, and public health education to reduce reproductive sequelae.

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