Jo’rayeva Gulhayo Jalol qizi (1)
Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, impaired insulin secretion, and progressive hyperglycemia. It represents one of the most widespread endocrine diseases worldwide and is associated with severe microvascular and macrovascular complications. Recent years have witnessed major advances in pharmacotherapy and patient-centered care, including the use of GLP-1 receptor agonists, SGLT2 inhibitors, and individualized treatment algorithms. This article reviews the modern methods of diagnosis and management of T2DM, emphasizing lifestyle modification, innovative pharmacological strategies, and the integration of digital technologies to improve patient outcomes and prevent long-term complications.
1. American Diabetes Association. (2024). Standards of Medical Care in Diabetes—2024. Diabetes Care, 47(Suppl 1), S1–S150.
2. DeFronzo, R. A., & Ferrannini, E. (2020). Pathogenesis of type 2 diabetes mellitus. Medical Clinics of North America, 104(5), 643–658.
3. Evert, A. B., Dennison, M., Gardner, C. D. (2023). Nutrition therapy for adults with diabetes or prediabetes. Diabetes Care, 46(5), 1080–1099.
4. Jo’rayeva, G. (2024). Combination of Diabetes and Metabolic Syndrome. Modern Science and Research, 3(12), 691–696.
5. Jo’rayeva, G. (2025). Risk Factors for the Development of Climacteric Disorders in Women with the Metabolic Syndrome. Modern Science and Research, 4(1), 1090–1092.
6. Jo’rayeva, G. (2025). The Role of Thyroid Hormones in Child Development. Modern Science and Research, 4(2), 990–995.
7. Jo’rayeva, G. (2025). Calcium Metabolism and Osteoporosis: The Role of the Endocrine System. Modern Science and Research, 4(3), 1155–1159.
8. Jo’rayeva, G. (2025). Strategies for Preventing Macro- and Microangiopathic Complications of Diabetes Mellitus. Modern Science and Research, 4(4), 1884–1892.