R.R. Khamrayeva, PhD (1)
Odontogenic infections range from minor abscesses to superficial and deep infections that can lead to acute infectious processes in the head and neck region and may pose a threat to the patient’s life. The aim of this study is to investigate the properties of bacteriophages capable of exerting a direct effect on bacteria responsible for infections of odontogenic origin. Bacteriophages—viruses capable of destroying bacteria—were discovered in 1915; however, with the advent of antibiotics, interest in their study has significantly declined. Their use in dentistry and maxillofacial surgery remains very limited to date. The purpose of this work is to systematize literature data on the possibility of using bacteriophages as part of комплекс treatment of purulent-inflammatory diseases of the maxillofacial region, as well as to identify the main directions of research aimed at evaluating the effectiveness of this treatment complex. The presented material indicates the necessity for further studies on the use of bacteriophages as part of complex treatment in patients with odontogenic purulent-inflammatory processes of the maxillofacial region. These studies should be conducted based on the principles of evidence-based medicine, using both established and newly proposed informative tests, and should be aimed at developing experimental, clinical, and laboratory justification for their application.
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