Assessment of Risk Factors for the Development of Osteoarthritis in Postmenopausal Women

Abstract

The prevalence of osteoarthritis (OA) among menopausal women and the continuous exacerbation of degenerative changes in the joints reduce the quality of imagination of female patients and determine the social and economic significance of the disease. In them, the specificity of clinical characteristics of OA and additional concomitant pathology of joint syndrome with continuous onset require a new approach to this disease, which creates the need for coordination in diagnosis and treatment. Endothelial dysfunction and hormonal imbalance during the menopausal period have been shown to induce adverse processes associated with OA that increase blood vessel spasm around the joint, increase blood supply and nutrition to the joint and slow destruction. In them, the specificity of the clinical characteristics of OA and the additional associated pathology of joint syndrome with continuous onset require a new approach to this disease.