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Study of the Prognostic Efficiency of Polymorphism Glu429ala in the Mthfr Gene in Women of the Uzbek Population with Congenital Defects of the Fetal Development

Vol. 2 No. 12 (2024): International Journal of Integrative and Modern Medicine:

Dilfuza Yangibaeva (1), Gulchehra Chorieva (2), Umida Sadullayeva (3)

(1) Department of Obstetrics and Gynecology in Family Medicine, Tashkent Medical Academy, Tashkent, Uzbekistan, Uzbekistan
(2) Department of Obstetrics and Gynecology in Family Medicine, Tashkent Medical Academy, Tashkent, Uzbekistan, Uzbekistan
(3) Department of Obstetrics and Gynecology in Family Medicine, Tashkent Medical Academy, Tashkent, Uzbekistan, Uzbekistan

Abstract:

The literature review summarizes modern ideas about the role of cytokines in the pathogenesis of osteoarthritis. Proinflammatory cytokines in joint tissue cause inflammation and damage ofvcartilage, leading to progressive joint degeneration.