DIFFERENTIAL IMMUNOCORRECTION IN WOMEN WITH GENITAL ENDOMETRIOSIS

Authors

  • Dildora Ismoilova Urgench branch of Tashkent Medical Academy Republic of Uzbekistan
  • Dilorom Musakhojaeva Republican Scientific Center of Immunology MHRUz Republic of Uzbekistan
  • Nargiza Magzumova Tashkent Medical Academy Republic of Uzbekistan
  • Gulmira Ahmedova Tashkent Medical Academy Republic of Uzbekistan

Keywords:

genital external and internal endome¬triosis, immune status, phagocytosis, cytokines.

Abstract

52 patients with genital endometriosis were exam­ined. Of these, 22 had internal endometriosis, and 30 had external genital endometriosis. 21 practically healthy women made up a control group. All examined women were examined the state of the immune system (cellular immunity, phagocytosis and cytokine status). It was found that in patients with endometriosis, the level of T-lymphocytes and its subpopulation composition were reduced, and the level of killer activity varied in different ways depending on the form of genital endome­triosis. Functional activity of neutrophils changed only in the group of women with EGE.

References

Ismailova D.U., Musakhodjaeva D.A., Magzumova N.M. External genital endometriosis in women and the rationale for differentiated immunocorrection. //Monograph. - .2022 .-- pp. - 153.

Ismailova D.U. Criteria for clinical immunological development of genital endometriosis in women and justification of differential immunocorrection. // Crosstalk Innate and Adaptive Immunity in Health and Disease. - 2021. - №6. - pp. 145.

Musakhodjaeva D.A., Magzumova N.M., Ismailova D.U. A method of immunocorrection in the complex therapy of genital endometriosis // Methodological recommendation. Ministry of Health No.8n-r/449 dated 10/30/2019. - 2019.-- pp. 153

Musakhodjayeva D.A., Aripova T.U., Fayzullayeva N.Ya., Ismailova D.U. An algorithm for assessing systemic immunity in women with genital endometriosis.// Methodological recommendation. Ministry of Health No.8n-r/450 dated 10/30/2019. - 2019.-- pp. 148.

Ismailova D.U., Musakhodjaeva D.A., Magzumova N.M. Changes in the subpopulation composition of lymphocytes in women with genital endometriosis// International Journal of Advanced Science and Technology Vol.29, No.5, -2020, - pp.2000-2007.

Ismailova D.U., Musakhodjaeva D.A., Magzumova N.M. Indicators of innate immunity in women with genital endometriosis. // International online conference “Topical issues of medical education, modern and innovative teaching methods”, May 6, - 2020. -pp. 91-94.

Ismailova D.U., Musakhodjaeva D.A., Magzumova N.M.. Changes in the parameters of the immune system in women with endometriosis.// Journal of Theoretical and Clinical Medicine., No. 1., - 2021., - pp. 93-95.

Ismailova D.U., Musakhodjaeva D.A., Magzumova N.M. Characteristics of clinical parameters in women with external endometriosis. // Collection of the International Scientific and Practical Conference Topical Issues of Medicine" and "IY Satellite Forum on Public Health and Health Policy". Azerbaijan-Baku. - 2022. – pp. 31-32.

Ismailova D.U., Musakhodjaeva D.A., Magzumova N.M. Changes in the immune system in women with endometriosis.// Journal of Theoretical and Clinical Medicine, No. 6.Volume 2, - 2021., - pp. 56-58.

Ismailova D.U., Musakhodjaeva D.A., Magzumova N.M. Differential immunocorrection in women with genital endometriosis.// Journal of Advanced Scientific Research (ISSN: 0976-9595) Vol.3. Issue 1. -2020 – pp. 48-54

Ismailova D.U. Changes in the immune system in women with genital endometriosis.// International scientific journal "Scientific Impulse" N°8 (100) part 3. March. - 2023. –pp. 99-103.

Musakhodjayeva D.A., Aripova T.U., Fayzullayeva N.Ya., Ismailova D.U. The level of cytokines in the peritoneal fluid in women with external genital endometriosis.// The 25 theWorld Congresson Controversiesin Obstetrics. Gynecology & Infertility (COGI).. - 2018 y . -- pp. 133.

Musakhodjaeva D.A., Magzumova N.M., Djumaeva D.N. Ismailova D.U. Correction of glucosaminylmuramyl dipeptide in the complex therapy of external genital endometriosis in women with infertility.// Collection of materials of the Republican scientific and practical conference with international participation "Topical issues of maternal and child health, achievements and prospects" -Ivanovo, -2018. --- pp. 41.

Ismailova D.U., Musakhodjaeva D.A., Magzumova N.M. The effectiveness of immunocorrective therapy in external genital endometriosis // Russian Immunological Journal.,Vol. 13 (22)., № 2., - 2019., -рp. 355-358.

Ismailova D.U., Musakhodjaeva D.A., Magzumova N.M. Immunotherapy fo infertility in women with small forms of genital endometriosis// Crosstalk Innate and Adaptive Immunity in Health and Disease. - 2018. - №6. - pp. 133.

Ismailova D.U. Endometriosis: diagnosis, treatment and rehabilitation // Methodical guide. -2023. – pp 33.

Yusupova M.A. Ismailova D.U. Assisted reproductive technologies (ART): // Methodical guide. -2020. – pp 36.

Musakhodjaeva D.A., Aripova T.U., Magzumova N.M, Fayzullayeva N.Ya., Ismailova D.U. et al. The subpopulation composition of lymphocytes in women with genital endometriosis.// Journal of Theoretical and Clinical Medicine”, -Toshkent, - 2018. - №6. - pp. 79-82.

Musakhodjaeva D.A., Aripova T.U., Magzumova N.M, Ismailova D.U. et al. Subpopulation composition of lymphocytes in women with genital endometriosis. // European Journal of Pharmaceutical and Medical Research, 5(5), - 2018, - pр.72-75.

Musakhodjaeva D.A., Aripova T.U., Magzumova N.M, Ismailova D.U. et al. Features of the immune system of women with genital endometriosis.// Russian Allergological Journal” , 2018, volume 15 No.1/part 2, - 2018. Moscow. - pp.13-15.

Ismailova D.U. Musakhodjaeva D.A., Magzumova N.M, Clinical and immunological criteria for the development of genital endometriosis in women and the justification of differentiated immunocorrection. // Along with the pressing problems of Medicine, the principles and methods of seducing children with tulips.Republican scientific practical conference with the participation of foreign scientists. - Urgench, 2018. - pp. 129-132

Krasilnikova A.K., Musakhodjaeva D.A,. Ismailova D.U. Sotnikova N.Yu., Malyshkina A.I., Antsiferova Y.S. A personalized approach to the treatment of infertility in small forms of genital endometriosis. // Journal of Theoretical and Clinical Medicine., No.4., - Moscow: -2018., -pp. 101-103.

Musakhodjaeva D.A., Magzumova N.M, Yeshimbetova G.Z., Ismailova D.U. et al. Immunocorrection in complex therapy in women with external genital endometriosis // Medical Review. vol.5. -Baku, - 2018. - pp. 103.

Abatangelo L., Okereke L., Parham-Foster C., Parrish C., Scaglione L., Zotte D., Taub L.F. If pelvic inflammatory disease is suspected empiric treatment should be initiated // J Am Acad Nurse Pract. - 2010. - N22(2). - pp.117-122.

Balamuth F., Jao H., Mollen C. Toward improving the diagnosis and the treatment of adolescent pelvic inflammatory disease in emergency departments: results of a brief, educational intervention // PediatrEmerg Care. - – 2010. - N26(2). - pp.85-92.

Bohler, N.S. et al. Endometriosis markers: immu¬nologic alterations as diagnostic indicators for en-dometriosis // Reprod. Sci. - 2007. - Vol. 14, №6. Adamyan, L.V.; Beloborodov, S.M.; Kholin, A. Modern principles of antimicrobial therapy of inflammatory diseases of the pelvic organs: (Literature review) // Problems of reproduction.-Moscow, 2005. - №6. - pp.31-38.

Buyanova S.N., Shchukina N.A., Gorshilin A.V. Reproductive prognosis in patients with purulent inflammatory diseases of the pelvic organs: problems and solutions // Russian Bulletin of obstetrician-gynecologist. - Moscow, 2009. - №2. - pp.65-68.

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Published

2024-06-09

How to Cite

Dildora Ismoilova, Dilorom Musakhojaeva, Nargiza Magzumova, & Gulmira Ahmedova. (2024). DIFFERENTIAL IMMUNOCORRECTION IN WOMEN WITH GENITAL ENDOMETRIOSIS. International Journal of Integrative and Modern Medicine, 2(6), 245–252. Retrieved from https://medicaljournals.eu/index.php/IJIMM/article/view/546