Sympatheadrenal System and Lipid Peroxidation Processes in Young People Employed in the it Profession

Despite national programs aimed at the prevention, early detection, and treatment of cardiovascular diseases, the problem remains highly relevant. In recent years, attention has been focused on the role of the sympathoadrenal system (SAS) in the pathogenesis of arterial hypertension. An acute release of catecholamines during stressful external influences is the earliest, due to stress and increased sympathetic nervous system tone, which is one of the key principles in the development of arterial hypertension in young people.

The aim of the study was to examine the characteristics of sympathoadrenal dysfunction and lipid peroxidation processes in young individuals working in the information technology field.

Materials and methods. Ninety men aged 25–44 years were examined; the average age was 33.2±0.93 years. Safe, instrumental, and distinctive laboratory research methods were used.

Results and Conclusions. It was established that young individuals actively working in the IT sector exhibit impaired sympathoadrenal system function, leading to increased excretion of catecholamines (primarily adrenaline and noradrenaline), disruption of the circadian rhythm of catecholamine excretion, decreased activity of monoamine oxidase (MAO), a key enzyme in catecholamine deamination, increased levels of vanillylmandelic acid, a quaternary metabolite of catecholamines, and increased levels of malondialdehyde (MDA), a secondary product of lipid peroxidation.