Hyperprolactinemia and Infertility: New Insights

Abstract

High serum prolactin levels define hyperprolactinemia which exists as a widespread endocrine medical condition. We identify this medical problem as a primary infertility factor since elevated prolactin reduces GnRH signals to cause irregular menstruation cycles and block ovulation and disturb the endometrium function. This paper provides an updated evaluation that explores both the origins and medical manifestation of hyperprolactinemia-associated infertility while discussing diagnosis procedures and treatment options. Research has examined both the mechanisms of GnRH inhibition by kisspeptin neurons while studying advances in treatment with dopamine agonists and surgical interventions and alternative therapeutic approaches. Knowledge about how hyperprolactinemia affects reproductive health stands essential to develop optimal fertility treatments together with superior pregnancy success rates.