Postoperative Complications in Neurosurgery: Risk Factors and Mitigation Strategies for Brain Tumor Patients

Authors

  • Dr. Mohammed Muneam Duhis M.B.Ch.B., A.B.H.S. \ (Neurosurgery) Lecturer, Iraqi Ministry of Higher Education and Scientific Research, University of Basra, Medical Collage, Basrah, Iraq | Iraqi Ministry of Health, Basrah Health Directorate, Mawani Teaching Hospital, Basrah, Iraq

Keywords:

Brain tumors, Neurological outcomes, Craniotomy surgery

Abstract

Background:

After brain tumor surgery, perioperative results are a crucial sign of the effectiveness and safety of the procedure.

Aim

This study is significantly discovered the evaluation of postoperative outcomes after neurosurgery as well as determining risk - factors of brain tumors at patients.

Methods

The surgical outcomes of 87 patients with brain tumors aged 4-40 years who underwent craniotomy in the neurosurgical departments of various hospitals in Basrah, Iraq, were documented in a recent study. The study enrolled postoperative outcomes, including mortality, complications, length of hospital stay, and other parameters. A general questionnaire was administered to assess postoperative quality of life, which evaluates the general health of brain tumor patients. The identification of patient-related risk factors was facilitated through a comprehensive review of clinical, demographic, and surgical characteristics.

Results

The current results showed infratentorial (17.24%) and supratentorial (82.76%), tumor size < 3 got 75.86%, glioma tumors with 68.97%, operation time ≥ 3 had 56.32%, hospital stay ≥ 6 days had 24.14%; mortality rate was 8.05%, postoperative complications had 34 cases, risk factors included duration of surgery, and tumor size, giloma, and emergency surgery, which are most factors affect patients.

Conclusion

Craniotomy surgery performs a critical role in the management for brain tumors, significantly changing patient health outcomes.

References

Black P, Golby A, Johnson M. The Emerging Field of Neurosurgical oncology: Novel techniques to optimize outcomes and minimize mishaps. Clin Neurosurg. 2007;54:36–46.

Sanai N, Berger MS. Glioma extent of resection and its impact on patient outcome. Neurosurgery. 2008;62:753–64.

Packer RJ, Vezina G. Management of and prognosis with medulloblastoma: Therapy at a crossroads. Arch Neurol. 2008;65:1419–24.

Kalkanis SN, Kondziolka D, Gaspar LE, Burri SH, Asher AL, Cobbs CS, et al. The role of surgical resection in the management of newly diagnosed brain metastases: A systematic review and evidence-based clinical practice guideline. J Neurooncol. 2010;96:33–43.

Pang BC, Wan WH, Lee CK, Khu KJ, Ng WH. The role of surgery in high-grade glioma--is surgical resection justified? A review of the current knowledge. Ann Acad Med Singapore. 2007;36:358–63.

Sawaya R. Extent of resection in malignant gliomas: A critical summary. J Neurooncol. 1999;42:303–5.

Ryken TC, Frankel B, Julien T, Olson JJ. Surgical management of newly diagnosed glioblastoma in adults: Role of cytoreductive surgery. J Neurooncol. 2008;89:271–86.

Moiyadi AV. Surgical management of malignant gliomas - Challenges and strategies. Int J Neurol Neurosurg. 2009;1:21–7.

Mangram AJ. Hospital infection control practices advisory Committee (HICPAC) and Centers for Disease Control and Prevention (CDC). Guidelines for prevention of surgical site infection. Infect Control Hosp Epidemiol. 1999;24:247–78.

Sawaya R, Hammoud M, Schoppa D, Hess KR, Wu SZ, Shi WM, et al. Neurosurgical outcomes in a modern series of 400 craniotomies for treatment of parenchymal tumors. Neurosurgery. 1998;42:1044–55.

Brell M, Ibáñez J, Caral L, Ferrer E. Factors influencing surgical complications of intra-axial brain tumours. Acta Neurochir (Wien) 2000;142:739–50.

Chang SM, Parney IF, McDermott M, Barker FG, 2nd, Schmidt MH, Huang W, et al. Perioperative complications and neurological outcomes of first and second craniotomies among patients enrolled in the Glioma Outcome Project. J Neurosurg. 2003;98:1175–81. doi: 10.3171/jns.2003.98.6.1175. [DOI] [PubMed] [Google Scholar]

Rabadán AT, Hernandez D, Eleta M, Pietrani M, Baccanelli M, Christiansen S, et al. Factors related to surgical complications and their impact on the functional status in 236 open surgeries for malignant tumors in a Latino-American hospital. Surg Neurol. 2007;68:412–20.

Stummer W, Pichlmeier U, Meinel T, Wiestler OD, Zanella F, Reulen HJ ALA-Glioma Study Group. Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: A randomised controlled multicenter phase III trial. Lancet Oncol. 2006;7:392–401.

Choudhari KA. Commentary: Surgery for glioblastoma and the influence of technology on outcomes between developed and developing parts of the world. Surg Neurol. 2010;73(2):e16.

Hossain MJ, Xiao W, Tayeb M, Khan S. Epidemiology, and prognostic factors of pediatric brain tumor survival in the US: evidence from four decades of population data. Cancer Epidemiol 2021;72:101942.

Bhakta N, Force LM, Allemani C, et al. Childhood cancer burden: a review of global estimates. Lancet Oncol 2019;20(01):e42–e53.

Udaka YT, Packer RJ. Packer RJJNc. Pediatric brain tumors. Neurol Clin 2018;36(03):533–556 4 Bathla G, Policeni B, Hansen MR, Berbaum K. Calculating the tumor volumes in vestibular schwannomas: are the ABC/2 and volumetric methods comparable? Otol Neurotol 2017;38(06): 889–894.

Louis DN, Perry A, Wesseling P, et al. The 2021 WHO classification of tumors of the central nervous system: a summary. Neuro-oncol 2021;23(08):1231–1251.

Palombi L, Marchetti P, Salvati M, Osti MF, Frati L, Frati A. Interventions to reduce neurological symptoms in patients with GBM receiving radiotherapy: from theory to clinical practice. Anticancer Res 2018;38(04):2423–2427.

Karschnia P, Vogelbaum MA, van den Bent M, et al. Evidence-based recommendations on categories for the extent of resection in diffuse glioma. Eur J Cancer 2021;149:23–33

Borchardt RA, Tzizik D. Update on surgical site infections: the new CDC guidelines. JAAPA 2018;31(04):52–54 9 Brouwer MC, Tunkel AR, van de Beek D. Epidemiology, diagnosis, and antimicrobial treatment of acute bacterial meningitis. Clin Microbiol Rev 2010;23(03):467–492.

Kimberlin DW. Red Book: 2018–2021 report of the committee on infectious diseases. American Academy of Pediatrics; 2018.

Haque M, McKimm J, Godman B, Abu Bakar M, Sartelli M. Initiatives to reduce postoperative surgical site infections of the head and neck cancer surgery with a special emphasis on developing countries. Expert Rev Anticancer Ther 2019;19(01):81–92.

Sattar F, Sattar Z, Zaman M, Akbar S. Frequency of post-operative surgical site infections in a Tertiary care hospital in Abbottabad, Pakistan. Cureus 2019;11(03):e4243.

Sáenz A, Badaloni E, Grijalba M, Villalonga JF, Argañaraz R, Mantese B. Risk factors for surgical site infection in pediatric posterior fossa tumors. Childs Nerv Syst 2021;37(10):3049–3056.

Sneh-Arbib O, Shiferstein A, Dagan N, et al. Surgical site infections following craniotomy focusing on possible post-operative acquisition of infection: prospective cohort study. Eur J Clin Microbiol Infect Dis 2013;32(12):1511–1516.

Lee RP, Venable GT, Vaughn BN, Lillard JC, Oravec CS, Klimo P Jr. The impact of a pediatric shunt surgery checklist on infection rate at a single institution. Neurosurgery 2018;83(03):508–520

Downloads

Published

2025-04-10

How to Cite

Duhis, D. M. M. (2025). Postoperative Complications in Neurosurgery: Risk Factors and Mitigation Strategies for Brain Tumor Patients. International Journal of Alternative and Contemporary Therapy, 3(4), 20–28. Retrieved from https://medicaljournals.eu/index.php/IJACT/article/view/1698

Similar Articles

<< < 2 3 4 5 6 7 8 > >> 

You may also start an advanced similarity search for this article.