ASSESSMENT OF ISCHEMIC PROCESSES IN PERIODONT TISSUE IN PATIENTS WITH HYPERTENSION

Abstract

Relevance of the study. Cardiovascular disease is one of the common causes of death. In addition, they are risk factors for triggering the atherosclerotic process. Nowadays, diseases in parodont tissues can also be considered a risk factor for cardiovascular diseases. In this, there will be inflammatory, immunological and humoral effects, which will form inflammatory cytokines and destroy the epithelium. This allows endotoxins and exotoxins to enter the bloodstream, which can cause atherogenesis as well as thromboembolic conditions. Changes in microcirculatory flow in hypertension can call ischemia in the periodont, which creates conditions for the development of a pathological process in periodontal tissues. In addition, endothelial dysfunction leads to the formation of an atherosclerotic rash as well as the development of lesions in the target organs. Periodontitis is also associated with insulin resistance as well as a high risk of developing metabolic syndrome, which is characterized by oxidative stress. It is this that explains the interdependence between each component of metabolic syndrome (including hypertension) and periodontitis . Periodontitis is a destructive disease that affects the basal structures of teeth, including the periodontal ligament, cement and the alveolar part of the bone. It is characterized by the presence of a chronic mixed infection called by several microbial agents (both Gram-negative and Gram-negative). Recent studies have shown that periodont diseases damage more than 50% of the total population. In turn, cardiovascular disease (YUTK) is the leading cause of death in developing and developed countries. For example, the incidence of cardiovascular disease in Brazil is 30% of total deaths and it responds to 1.2 million hospitalizations. Therefore, these clinical conditions are the most common disease among the adult population, which makes the prevention and treatment of YUTK an important strategy of the global health system. The study of cases showing a link between chronic periodontitis and cardiovascular disease was carried out with a secondary analysis of the data. These studies have shown that people who have PD are susceptible to high risk of cardiovascular disease, namely: stroke, ischemic heart disease (YUIK), etc. Hypertension is the most common disease among all cardiovascular diseases and covers 30-40% of the large population. The atherosclerotic process, called by typical cardiovascular risk factors, manifests itself in the anatomical substrate for the development of primary cardiovascular disease. However, despite all the recommendations for the prevention and treatment of this disease, atherosclerosis continues to develop, which leads to an increase in fatal cases of cardiovascular disease. PD is common throughout the population today. Although PD is another cardiovascular risk factor, it has not been well studied by cardiologists [1.3.5.7.9.11.13.14].