CLINICAL EVALUATION OF PATHOLOGICAL CHANGES IN PATIENTS WITH CARDIOVASCULAR DISEASE

Relevance of the study. In patients with cardiovascular diseases, the etiological structure of infection processes has changed significantly in the last decade, which is due to the constant evolution of microbes and the involvement of conditional-pathogenic microbes in the pathological process as commensals in the composition of normal microflora and can manifest their pathogenicity when the immune state in the body decreases. Data from studies indicate that inflammatory processes in the oral cavity are sometimes detected not only in the oral cavity, but also in other systems of the body with endogenous infection, which is called due to resident flora. In patients with cardiovascular diseases, periodontopathologies change the composition of microflora and microorganisms that are part of the oral cavity during the development of inflammation. At an early stage of the disease, it is possible to observe a decrease in normal microflora and the appearance of conditionally-pathogenic bacteria. Over time, an increase in pathogenic microorganisms occurs in the tissues of the parodont, which leads to purulent processes. In patients with cardiovascular disease, periodontopathologies have confirmed that inflammatory diseases are accompanied by oral dysbiosis. The signs and accuracy of the clinical picture correspond to the degree of damage to the parodont, as a result of which the growth of pathogenic and conditional-pathogenic microorganisms occurs, and the quantitative composition of normal microorganisms decreases [2.4.6.8.10.12.14].