Peculiarities of the Clinical Picture, Pathogenesis and Drug Treatment of Secondary Phacogenic Glaucoma

Authors

  • Sabirova Dilrabo Baxodirovna Samarkand State Medical University, Department of Ophthalmology

Keywords:

intraocular pressure, glaucoma, cataract, lens, luxation

Abstract

Pathologies of the lens often lead to increased intraocular pressure and the development of secondary glaucoma. The article presents a description of the clinical picture and pathogenetic aspects of the development of various forms of secondary phacogenic glaucoma: phacotopic, phacomorphic and phacolytic. A scheme of intensive drug therapy aimed at reducing intraocular pressure and neuroprotection of the retina is proposed. Based on the results of the study, an assessment of the effectiveness of hypotensive treatment was made, as well as the possibility of long-term drug control of ophthalmotonus against the background of lens pathologies. Ophthalmological examinations were performed in daylight, artificial light, and in the dark. Results and discussion. Studying the risk factors for secondary glaucoma, it was found that in 55 out of 142 patients (39% of cases), the development of secondary glaucoma was associated with lens pathologies (phacogenic glaucoma): luxation or subluxation of the lens, swelling cataract, lysis of hypermature cataract. Diagnostic criteria and clinical picture of glaucoma of phacogenic etiology were studied in 55 patients (68 eyes – 100%). Average IOP values during tonometry were 37.13 ± 4.45 mm Hg. The study revealed that in 42 out of 55 patients (42 eyes – 76.4% of cases) secondary glaucoma against the background of lens pathologies was noted unilaterally. In 13 patients (26 eyes – 23.6% of cases) phacogenic secondary glaucoma was noted bilaterally.

References

Alencar, L. M. The role of standard automated perimetry and newer functional methods for glaucoma diagnosis and follow-up / L. M. Alencar, F. A. Medeiros / Indian Journal of Ophthalmology. - 2011. - Vol. 59, № 7. - P. 53-58.

Artes, P. H. Properties of the statpac visual field index / P. H. Artes, N. O'Leary, D. M. Hutchison, L. Heckler [et al.] / Investigative Ophthalmology & Visual Science - 2011. - Vol. 52. - P. 4030-4038.

Bengtsson, B. False-negative responses in glaucoma perimetry: indicators of patient performance or test reliability? / B. Bengtsson, A. Heijl / Investigative Ophthalmology & Visual Science. - 2000. - Vol. 41. - P. 2201-2204.

Bengtsson, B. Inter-subject variability and normal limits of the SITA Standard, SITA Fast, and the Humphrey Full Threshold computerized perimetry strategies, SITA STATPAC / B. Bengtsson, A. Heijl / Acta Ophthalmologica. - 1999. - № 77. - P. 125-129.

Bengtsson, B. Diagnostic sensitivity of fast blue-yellow and standard automated perimetry in early glaucoma: a comparison between different test programs / B. Bengtsson / Ophthalmology. - 2006. - Vol. 113, № 7. - P. 1092-1097.

Boland, M. V. Evaluation of Frequency-Doubling Technology Perimetry as a Means of Screening for Glaucoma and Other Eye Diseases Using 127 the National Health and Nutrition Examination Survey / M. V. Boland, P. Gupta, F. Ko, D. Zhao [et al.] / JAMA Ophthalmology. - 2016. - Vol. 134, № 1. - P. 57-62.

Breusegem, C. Variability of the standard reference height and its influence on the stereometric parameters of the Heidelberg Retina Tomograph 3 / Investigative Ophthalmology & Visual Science. - 2008. - Vol. 49, № 11. - P. 4881-4885.

Brusini, P. Clinical use of a new method for visual field damage classification in glaucoma. / Eur J Ophthalmol. - 1996. - Vol. 6. - P. 402-407.

Budenz, D. L. Determinants of normal retinal nerve fiber layer thickness meashured by Stratus OCT / Ophthalmology. - 2007. - Vol. 114, № 6. - P. 1046-1052.

Centofanti, M. Learning effect of Humphrey Matrix Frequency Doubling Technology perimetry in patients with ocular hypertension / M. Centofanti, P. Fogagnolo, F. Oddone / Glaucoma. - 2008. - Vol. 17, № 6. - P. 436-441.

Chauhan, B. C. Technique for detecting serial topographic changes in the optic disc and peripapillary retina using scanning laser tomography / Investigative Ophthalmology & Visual Science. - 2000. - Vol. 41. - P. 775-782.

Coleman, A. L. Risk factors for glaucoma onset and progression / Survey of Ophthalmology. - 2008. - Vol. 53, № 1. - Р. 3-10.

Сабирова, Д. Б., Юсупов, А. А., Искандаров, Ш. Х., Кадырова, А. М., & Тулакова, Г. Э. Клиническая оценка озонотерапии и криопексии у пациентов с герпетическим кератитом // Точка зрения. Восток–Запад, (2016). (1), 147-149. 13. Сабирова, Д. Б., Тулакова, Г. Э., & Эргашева, Д. С. Комплексное лечение диабетической макулопатии путем применения пептидного биорегулятора" Ретиналамин" и лазеркоагуляции сетчатки // Точка зрения. Восток-Запад, (2017). (2), 114-116.

Сабирова, Д. Б., Искандаров, Ш. Х., Косимов, Р. Э., Эргашева, Д. С., & Юсупов, А. А. Совершенствование лечения герпетических кератитов с использованием озона в виде газа через очки аппарата" Орион-си" // Российский общенациональный офтальмологический форум, (2015). 1, 159-163. EUROPEAN JOURNAL OF MODERNMEDICINE AND PRACTICE Vol. 4 No. 8 (Aug - 2024) ISSN: 2795-921X 174

Сабирова, Д. Б., Облоёров, И. Х., & Хазратова, Д. Ф. КЛИНИКО-ЭПИДЕМИОЛОГИЧЕСКИЕ ОСОБЕННОСТИ ВЕСЕННЕГО КАТАРА И ЛЕЧЕНИЕ ИММУНОКОРРЕГИРУЮЩИМИ СРЕДСТВАМИ // НАУЧНЫЕ ИССЛЕДОВАНИЯ, (2019).52.

Тулакова, Г. Э., Сабирова, Д. Б., Хамракулов, С. Б., & Эргашева, Д. С. Отдалённые результаты ксеносклеропластики при миопии высокой степени // Научный форум. Сибирь, (2018). 4(1), 80- 80. 17. Юсупов, А. А., Бобоев, С. А., Хамракулов, С. Б., Сабирова, Д. Б., & Косимов, Р. Э. Взаимосвязь функциональных и анатомо-оптических параметров глаза при врожденной близорукости // Вопросы науки и образования, (2020). (22 (106)), 44-53.

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Published

2025-01-11

How to Cite

Baxodirovna, S. D. (2025). Peculiarities of the Clinical Picture, Pathogenesis and Drug Treatment of Secondary Phacogenic Glaucoma. International Journal of Integrative and Modern Medicine, 3(1), 61–69. Retrieved from https://medicaljournals.eu/index.php/IJIMM/article/view/1444