Polycystic Ovary Syndrome and Hypothyroidism in Women Living in the Andijan Region
Keywords:
PCOS, hypothyroidism, reproductive healthAbstract
Polycystic ovary syndrome (PCOS) and hypothyroidism are among the most common endocrine disorders affecting women of reproductive age. These conditions often coexist and have overlapping clinical and metabolic manifestations. The Andijan region of Uzbekistan is known for a high prevalence of iodine deficiency and thyroid disorders. This study investigates the association between PCOS and hypothyroidism among women residing in this region. We conducted a prospective cross-sectional analysis of 120 women aged 18–45 years presenting with menstrual irregularities, infertility, or signs of hyperandrogenism. The study revealed a significant overlap between PCOS and hypothyroidism, emphasizing the importance of integrated endocrine evaluation and management strategies in such populations.
References
Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. (2004). Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome.
Azziz R et al. (2016). Polycystic ovary syndrome. Nature Reviews Disease Primers, 2(1), 16057.
Unnikrishnan AG et al. (2013). Prevalence of hypothyroidism in adults: An epidemiological study in eight cities of India. Indian J Endocrinol Metab, 17(4), 647–652.
Rosenfield RL. (2007). Clinical practice. Hirsutism. N Engl J Med, 357(12), 1225–1236.
Oerbeck B et al. (2003). Iodine deficiency and hypothyroidism in Central Asia: Focus on Uzbekistan. Thyroid, 13(10), 919–928.
Baloch Z et al. (2003). Laboratory medicine practice guidelines for the diagnosis and monitoring of thyroid disease. Thyroid, 13(1), 3–126.
Dunaif A. (1997). Insulin resistance and the polycystic ovary syndrome: Mechanism and implications for pathogenesis. Endocr Rev, 18(6), 774–800.
Ganie MA et al. (2010). Hypothyroidism in polycystic ovary syndrome: Relevance of clinical evaluation. Indian J Endocrinol Metab, 15(4), 294–298.
