Diagnostics and Differential Diagnostics of Urolithiasis and Renal Form of Primary Hyperparathyroidism in Children

children urolithiasis primary hyperparathyroidism (PHPT) renal form (RF) mixed form (MF) urinary stone disease (USD)

Authors

  • F.F. Bayakhmedov Diagnostics And Differential Diagnostics Of Urolithiasis And Renal Form Of Primary Hyperparathyroidism In Children
  • A.A. Nasirov Diagnostics And Differential Diagnostics Of Urolithiasis And Renal Form Of Primary Hyperparathyroidism In Children
April 30, 2025

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It has been established that differential diagnostics of renal form of primary hyperparathyroidism (PHPT) is based on detection of phosphorus-calcium metabolism disorders, the most sensitive and effective is carrying out of loading tests. For the first time it is shown that renal failure in patients with RF PHPT aggravates the imbalance of hormones regulating calcium homeostasis, and indicates a marked impairment of the functional activity of the parathyroid glands (PGG). Kidney dyMFunction in children with USD had no significant effect on the level of calcium-regulating hormones. Diagnostic criteria and differential diagnostics of RF PHPT have been scientifically substantiated; as a result, a diagnostic algorithm of USD and RF PHPT has been created.

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